Profluent
Biomedicine
SustainingAssociateEngineer-EngineerI,HighThroughputOperations
Neural analysis suggests this role is
optimal for Mid+ candidates.
“Sustaining Associate Engineer - Engineer I, High Throughput Operations at Profluent. Skills: High throughput operations, Automation equipment maintenance, Lab equipment troubleshooting. Provide onsite operator support. Perform regular maintenance”
Industry & Context.
Troubleshooting; Analytical skills; Critical thinking
What They're Looking For.
Must Have
BS/MS in science or engineering, 1-3 years relevant experience, Hands-on operating liquid handling systems, Familiarity with HTP assay development, Familiarity with gene assembly workflows, Familiarity with cloning workflows, Familiarity with mammalian screening workflows, Familiarity with NGS workflows, Adapt to changing project priorities, Adapt to changing timelines, Oral communication skills, Written communication skills, Excellent analytical skills, Critical thinking skills
Nice to Have
Familiarity with gene editing systems, Familiarity with genome-wide assays, Experience working with external vendors, Experience working with third-party service providers, Service trained in automation platforms, Service trained in HTP lab equipment, Experience with asset management systems, Experience with ticketing systems
What You'll Do.
Provide onsite operator support
Perform regular maintenance
Troubleshoot liquid handlers
Troubleshoot high throughput lab equipment
Troubleshoot integrated systems
Write verification test protocols
Write validation test protocols
Deliver IQ/OQ/PQ reports
Support development of SOPs
Support development of reports
Assist with implementation
Develop tools for tracking spare parts
Develop tools for tracking service calls
Develop tools for tracking repairs
Develop reporting for spare parts
Develop reporting for service calls
Develop reporting for repairs
Develop operational documents for spare parts
Develop operational documents for service calls
Develop operational documents for repairs
Build relationships with vendors
Build relationships with third-party service providers
Maintain relationships with vendors
Maintain relationships with third-party service providers
How You'll Work.
Team & Collaboration
Cross-functional teams; Work with stakeholders
Communication Scope
Oral communication; Written communication
Full Job Description
Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date. We are seeking a motivated and creative Sustaining Engineer to join our High Throughput Operations team. The focus of this role will be to maintain automation equipment, assist in day-to-day high throughput activities, and contribute to building equipment maintenance and service tracking infrastructure for our in-house molecular cloning, mammalian screening and NGS cores. This role is vital to ensuring that we can quickly build, productionize, and provide thorough support for the automated workflows used by Biology project teams to accelerate discoveries across the life sciences. This is an excellent opportunity to shape the future of AI-driven protein design and to work cross-functionally with a diverse team of experts across machine learning, protein engineering, cell biology, and gene editing. Responsibilities Provide onsite operator support for automated workflows Provide regular maintenance, calibration, and troubleshooting procedures on liquid handlers, high throughput lab equipment, and other integrated systems Write verification and validation test protocols and deliver reports including IQ/OQ/PQ Support the development of SOPs and reports for validated automation processes and assist with implementation Develop tools, reporting and operational documents for tracking equipment spare parts, service calls, and repairs Build and maintain relationships with vendors and third-party service providers Qualifications BS/MS in science or engineering discipline with 1-3 years of relevant experience Hands-on experience operating liquid handling systems (e. g. T
Applying for this Sustaining Associate Engineer - Engineer I, High Throughput Operations role?
Most applicants get filtered before a human reads their resume. See if yours makes the cut.
How to Apply on Greenhouse
- Create a Greenhouse profile before applying — it saves time across multiple applications.
- Upload your resume as a PDF; the parser handles it better than Word.
- Answer all knockout questions carefully — wrong answers auto-reject before a human sees you.
- Enable email notifications to track application status in real time.
ANONYMOUS · UNFILTERED
What do employees actually say about Profluent?
Real rants from real employees. Read before you apply.