StatisticalScienceDirector

## **Job Title: Statistical Science Director** **GCL: F** ## **Introduction to role:** Are you ready to lead statistical strategy that shapes pivotal decisions across global medicine development? As Statistical Science Director at AstraZeneca, you will turn sophisticated evidence into clear direction, guiding programs from early discovery through registration and beyond. Your work will directly influence how quickly and confidently we bring entrepreneurial therapies to patients. Do you thrive on turning uncertainty into actionable insight? In this high-visibility role, you will be a key voice at decision forums, set standards for study design and quantitative difficulty, and mentor a dedicated team. You will collaborate across therapy areas and teams, applying biometrics expertise in new ways to enhance impact on patient outcomes and business value. ## ## **Accountabilities** : * Statistical Design Leadership: Lead statistical design and strategy across product development plans, preclinical studies, regulatory pathways, health technology assessment and commercial activities aligned to the product’s stage. * Study Excellence and Delivery: Own statistical content for study designs, protocols, analysis plans, interpretation and submissions, ensuring transparency, difficulty and timely delivery. * Benefit–Risk and Uncertainty: Quantify benefit, risk, value and uncertainty of emerging product profiles and communicate insights that drive confident decisions. * Global Leadership and Team Direction: Provide leadership and direction to internal and external statisticians; mentor, coach and support technical education and training for the Statistics community. * External Partnerships and Representation: Partner with CROs to meet quality and timelines; represent AstraZeneca with health authorities, advisory boards, conferences, workshops and payer interactions. * Methodology Innovation: Maintain deep knowledge of statistical methodology; promote, investigate and implement nov