Regeneron

Pharmaceutical

SrStaffEngineer,SyntheticandBioconjugationScaleUpTechnologies(PMPD)

$151–246k Tarrytown, New York, United States FULL TIME
The Brief

“Sr Staff Engineer, Synthetic and Bioconjugation Scale-Up Technologies (PMPD) at Regeneron. Skills: Bioconjugation scale-up, GMP-ready processes, Technology transfer documentation. Design scalable processes. Develop scalable processes”

Industry & Context.

Pharmaceutical
Problems you'll solve

Problem-solving skills

Eligibility Requirements

Up to 20% travel

What They're Looking For.

Must Have

Ph.D. or Master's in organic chemistry, Master's degree with 120+ years experience, BS with 15+ years experience, 5 years industrial experience post-PhD, 7 years experience post-Masters

Nice to Have

Experience with small-molecules in bioconjugates, Experience with solid-phase peptide synthesis, Proven experience scaling-up synthetic small-molecule reactions, Experience with solid-phase oligonucleotide synthesis, Experience with oligonucleotide purification, Experience with oligonucleotide characterization

What You'll Do.

Design scalable processes

Develop scalable processes

Develop robust processes

Develop controlled GMP-ready processes

Develop processes for chemical synthesis

Develop processes for small-molecules

Develop processes for oligonucleotides

Develop purification development

Establish analytical characterization techniques

Comply to environmental safety

Work with R&D chemistry

Work with Formulations Development

Work with Analytical Chemistry

Work with Protein Biochemistry

Generate technology transfer documentation

Support production during scale-up

Support GMP manufacturing

Partner with External Manufacturing

Develop new technologies

Develop predictive process models

Pioneer at-line process analytical technologies

Pioneer in-line process analytical technologies

Ensure robust processing

Review regulatory submissions

Provide domain expertise

Author tech transfer documents

Author regulatory support documents

Perform long-term planning

Plan laboratory personnel

Plan laboratory supplies

Plan laboratory equipment

Design cGMP-ready processes

Develop isolation processes

Ensure team-based evaluation

Work with key stakeholders

Promote new technologies

Provide domain expertise for submissions

How You'll Work.

Team & Collaboration

Team-based evaluation; Work with R&D chemistry; Work with Formulations Development; Work with Analytical Chemistry; Work with Protein Biochemistry; Partner with External Manufacturing; Work with key partners; Work with IOPS organization; Work with CDMOs; Work with key stakeholders

Communication Scope

Verbal communication; Written communication

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