Sr.ResearchAssociate,ProteinDesign

**The Role** Moderna is seeking a Senior Research Associate to join the Protein Design team at its Cambridge, MA site. This role will primarily support protein expression screening and characterization for the Infectious Disease Research. The candidate will be responsible for utilizing mammalian cell culture techniques for protein expression, applying chromatographic methods for protein purification, and performing biophysical characterization of proteins to support the development of vaccines and therapeutics. Strong collaboration and problem-solving skills are essential, as the candidate will align on project goals and deliver high-quality results to drive the progress of multiple research programs. This is an exciting opportunity to contribute to cutting-edge vaccine and therapeutic development in a fast-paced and innovative environment. **Here 's What You’ll Do** * Mammalian cell culture and protein expression primarily in mammalian cells; * Protein purification by chromatography-based methods (affinity, ion exchange, size-exclusion, use of FPLC systems for semi-automated purifications) * Testing and optimizing expression/purification conditions * Characterization of proteins by standard biochemical and biophysical techniques (SDS-PAGE, western blots, DSC, DSF, SEC-MALS) * Manage an inventory of laboratory reagents and support logistics of external receipts/shipping for partnered programs * Interpret, summarize, and present experimental data and results at group meetings, project meetings and department meetings * Assess protein expression via flow cytometry-based approaches * Experience with techniques such as BLI and SPR to study biomolecular interactions * Experience working with or knowledge of viral vaccine antigens * Research and develop new protein purification methods, and scout other enabling technologies to facilitate production of difficult-to-express proteins * Effectively communicate project goals, timelines, progress, and results across functional