Moderna

Biotech

Sr.ResearchAssociate,NGSplatform

$74–118k Cambridge, Massachusetts, United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Sr. Research Associate, NGS platform at Moderna. Skills: NGS platform, Genomic analysis, Molecular biology. Develop and optimize NGS library preparation methods. Perform library preparation and sequencing”

Industry & Context.

Biotech
Problems you'll solve

Troubleshoot experimental issues

What They're Looking For.

Must Have

5+ years of experience in NGS, BS/MS degree in a relevant scientific discipline, Experience with library preparation, Experience with sequencing platforms, Experience with data analysis

Nice to Have

PhD in a relevant scientific discipline, Experience with automation, Experience with bioinformatics tools

What You'll Do.

Develop and optimize NGS library preparation methods

Perform library preparation and sequencing

Analyze sequencing data

Troubleshoot experimental issues

Maintain laboratory equipment

Document experimental procedures

Collaborate with research teams

Stay current with NGS technologies

How You'll Work.

Team & Collaboration

Research teams; Cross-functional teams

Full Job Description

**The Role** In this role, you will be a key contributor within the Genome Sciences team, supporting efforts across Moderna’s mRNA platform to advance therapeutic programs and impact patients. You will own and execute end-to-end next-generation sequencing (NGS) workflows, from nucleic acid extraction through library preparation, sequencing, and data QC. Your work will generate high-quality, decision-driving datasets that directly inform platform research and therapeutic program advancement. This team operates in a hybrid model – a centralized genomics platform with the flexibility to embed within project teams as needed – supporting work that ranges from single-sample, high-complexity studies to high-throughput production workflows. We operate with a shared ownership mindset: collective responsibility for platform success, paired with individual ownership of execution, troubleshooting, and continuous improvement. The ideal candidate brings strong molecular biology expertise, hands-on NGS experience, and a collaborative, shared-ownership mindset, with the ability to independently troubleshoot, adapt, and scale assays in a fast-paced environment. Experience with downstream molecular and/or cell-based assays is a plus. The candidate must thrive in a fast pace environment with high expectations. Integrity, ability to share experimental issues and troubleshoot, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team. **Here’s What You Will Do** * Own nucleic acid extraction workflows from diverse samples, leveraging automated liquid handling systems * Ensure sample quality through accurate quantification, qualification, and normalization * Prepare RNA and DNA sequencing libraries using kit-based and custom workflows * Perform library QC, pooling, and sequencing setup for Illumina and Nanopore platforms * Operate and maintain sequencing instruments to ensure consistent performance and uptime *

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