AstraZeneca
Healthcare
SeniorStatisticianII
Neural analysis suggests this role is
optimal for Senior candidates.
“Senior Statistician II at AstraZeneca. Skills: Statistics, Study Design, Statistical Analysis, Drug Development. Provide statistical expertise for study designs. Analyze internal and external data”
What You'll Achieve.
Accelerate therapies to patients; Influence regulatory outcomes; Influence clinical outcomes; Influence commercial outcomes; Smarter study designs; Sharper submissions; Faster development decisions; Better informed development decisions; Advance science; Advance patient outcomes; Raise quality; Raise efficiency; Raise reproducibility
Industry & Context.
Solve real-world questions; Apply statistical expertise; Problem solving
What They're Looking For.
Must Have
MSc/PhD in Statistics, MSc in Mathematics, Competent statistical programmer, SAS and R proficiency, Knowledge of technical requirements, Knowledge of regulatory requirements, Experience in study design, Experience in analysis of studies, Experience in reporting of studies, Experience in preclinical studies, Experience in clinical studies, Experience in multiple settings, Experience applying statistical expertise, Problem solving skills, Quality focus
Nice to Have
Experience contributing to regulatory interactions, Authoring statistical components of submissions, Methodological research track record, Publications track record, Conference presentations track record, Proficiency with Bayesian methods, Proficiency with causal inference, Proficiency with adaptive trial designs, Proficiency with innovative trial designs, Proficiency with real-world evidence generation, Familiarity with Python, Familiarity with version control, Familiarity with reproducible pipelines, Experience mentoring statisticians, Experience leading statistical strategy discussions, Exposure to decision science, Exposure to program-level simulations, Exposure to portfolio optimization, PhD preferred
What You'll Do.
Provide statistical expertise for study designs
Analyze internal and external data
Develop Statistical Analysis Plans
Analyze study results
Interpret study results
Summarize study results
Translate findings into insights
Specify statistical components of submissions
Craft responses to regulatory questions
Guide statisticians in producing analyses
Guide statisticians in producing graphics
Guide statisticians in producing tables
Cultivate best practices
Cultivate shared standards
Identify opportunities to enhance design
Identify opportunities to enhance delivery
Investigate new statistical techniques
Apply new statistical techniques
Iterate pragmatic solutions
Refine pragmatic solutions
Build collaborative links with external scientists
Contribute to conferences
Contribute to journals
Be accountable for quality
Provide constructive challenge
Lead process improvements
Contribute to process improvements
Lead capability improvements
Contribute to capability improvements
How You'll Work.
Team & Collaboration
Collaborate across disciplines; Collaborate with clinicians; Collaborate with regulators; Collaborate with business partners; Collaborate with external scientists; Cross-functional statistical strategy
Communication Scope
Results interpretation; Clear communication; Actionable insights; Regulatory questions; External engagement; Thought leadership
Full Job Description
Are you ready to turn complex data into decisions that shape the future of medicines? Do you want your statistical leadership to accelerate therapies to patients and influence high‑stakes regulatory, clinical, and commercial outcomes? As a Senior Statistician II at AstraZeneca, you will own critical design and interpretation work across preclinical and clinical programs, providing the evidence and clarity that move assets forward. You will operate independently on challenging problems, mentor others, and collaborate across disciplines to solve real-world questions in drug development. Your impact will be felt in study designs that are smarter, submissions that are sharper, and development decisions that are faster and better informed. You will join a global R&D community that values curiosity and courage—where digital, data science, and AI are fused with deep biology to push past the expected. Here, you will explore new methodologies, engage with external experts, and contribute to publications as your work advances science and patient outcomes. **Accountabilities:** * Study Design Leadership: Provide statistical expertise for complex study designs across preclinical and clinical programs, ensuring high-quality decision-making for governance forums, regulatory submissions, and commercialization. * Modeling and Simulation for Decisions: Analyze internal and external data, build models, and run simulations to inform design choices and decision criteria that de-risk development and optimize investment. * Statistical Analysis Planning: Develop rigorous Statistical Analysis Plans for complex studies and cross-study project deliveries, aligning methods to clinical and scientific objectives. * Results Interpretation and Communication: Analyze, interpret, and summarize complex study results, translating findings into clear, actionable insights for clinicians, regulators, and business partners. * Regulatory Excellence: Contribute to submissions by specifying statistical comp
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