Prolific Machines

Biotechnology

SeniorSoftwarePlatformEngineer

$160–210k Emeryville, California, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Senior Software Platform Engineer at Prolific Machines. Skills: Software platform, Hardware/software boundary, Cloud infrastructure, Internal tooling. Architect software platform. Develop software platform”

Industry & Context.

Biotechnology
Problems you'll solve

Systems thinking; Debugging

What They're Looking For.

Must Have

MS with 5+ years experience, BS with 7+ years experience, Systems-level thinking, Balance rapid prototyping with scalability, Decompose complex systems, Fluency in Python, Proficiency in one other language, Define, design, implement, deploy software, Design for reliability and maintainability, Deploy cloud-connected applications, Experience with SQL databases, Work with end users, Set up development environment, Interface software with hardware, Debug software/hardware boundary, Comfort working in Linux

Nice to Have

Experience leading technical projects, Exposure to Industrial IoT / Industry 4.0, Experience with electronic records, Experience in biotech/pharma, Experience modernizing operational tooling, Experience developing custom dashboards, Expertise in devops workflows, Embedded C/C++ development, Knowledge of firmware limitations, Experience with Ignition, Experience with AirTable, Experience with Particle Cloud

What You'll Do.

Architect software platform

Develop software platform

Define software interfaces

Define communication layers

Define subsystem boundaries

Collaborate with firmware engineers

Collaborate with hardware engineers

Design hardware/software interactions

Establish scalable software infrastructure

Establish engineering practices

Define technical scopes

Define development strategy

Contribute hands-on across stack

Shape software technical direction

How You'll Work.

Team & Collaboration

Multidisciplinary team; Firmware engineers; Hardware engineers; Data engineers; Bioprocess engineers; Scientists; Operators

Communication Scope

Technical documentation

Process & Methodology

Roadmap planning

Full Job Description

## Description Prolific Machines is ushering in a new era of biotechnology with light. Our mission is to make next-generation therapies broadly available to patients. Our first-of-its-kind Photomolecular Platform uses light to precisely guide how cells produce complex biologics, enabling higher titers, improved quality, and faster development timelines. By helping partners overcome today’s manufacturing bottlenecks, we’re accelerating the delivery of life-changing medicines. Prolific is supported by leading investors, including Bill Gates’s Breakthrough Energy Ventures, Mayfield, and SOSV.   Help us create a brighter tomorrow with biology. We're looking for mission-driven, talented, and kind people to join our team. This is a high-ownership role with significant opportunity to shape the long-term direction of software systems at Prolific. As a foundational Software Engineer within the organization, you will have substantial influence over architecture, tooling, and long-term technical direction. We’re looking for a Software Engineer to help define and build the next-generation software and controls platform underlying Prolific’s illumination systems. This role will serve as a foundational software hire within a multidisciplinary illuminator technology team, helping define software architecture across device control, cloud-connected infrastructure, internal tooling, and future customer-facing systems. This individual will work closely with Firmware, Hardware, Data, and Bioprocess Engineering teams to develop scalable, production-ready control systems for next-generation illumination products. Over time, this role is expected to help define software architecture, interfaces, and development strategy as Prolific expands both internal software capabilities and external development partnerships. This is not a traditional consumer web or SaaS role. Success in this position requires strong systems thinking and comfort operating across the hardware/software boundary. The id

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