Heartflow

Healthcare

SeniorSoftwareEngineer

$175–250k ~AI est. San Francisco, California, United States
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Senior Software Engineer at Heartflow. Skills: Agentic AI, LLM integration, Platform infrastructure, Medical device software. Own core AI platform infrastructure. Build shared libraries”

Industry & Context.

Healthcare
Problems you'll solve

Root cause analysis; Debugging; Troubleshooting

What They're Looking For.

Must Have

7+ years relevant industry experience, Proficiency in Python, Proficiency in TypeScript, Deep experience with FastAPI, Proficiency in React, Hands-on experience with AWS, Hands-on experience with Terraform, Experience with Agile methodologies, Experience with project management tools, Deep understanding of LLM API integration, Deep understanding of prompt engineering, Deep understanding of RAG orchestration, Production experience building deterministic tool integrations, Experience with Docker, Experience with RESTful APIs, Experience with Git, Experience with CI/CD pipelines

Nice to Have

Experience with high-performance languages, Advanced experience fine-tuning open-weight models, Deploying local models with PyTorch, Deploying local models with Hugging Face, Hands-on experience with LangGraph, Hands-on experience with Pydantic AI, Experience with multi-agent browser automation, Experience with AI-specific adversarial testing, Experience with prompt security, Familiarity with serverless architecture, Familiarity with Kubernetes, Familiarity with vector databases, Background in MedTech regulatory frameworks

What You'll Do.

Own core AI platform infrastructure

Build shared libraries

Maintain shared libraries

Build MCP tool integrations

Maintain MCP tool integrations

Build deployment pipelines

Maintain deployment pipelines

Apply AI to software development

Use LLMs to accelerate SDLC

Parse product requirements

Map requirements to modules

Auto-generate test cases

Design Human-in-the-Loop workflows

Architect HITL workflows

Build knowledge retrieval architecture

Design retrieval pipelines

Connect Claude to tools

Develop MCP host environments

Maintain MCP host environments

Develop client applications

Maintain client applications

Build evaluation systems

Create automated evaluation harnesses

Integrate LLM-as-a-judge pipelines

Validate AI output quality

Build sophisticated agentic frameworks

Combine foundation models

Create internal developer tooling

Build DX infrastructure

Translate between teams

How You'll Work.

Team & Collaboration

World-class researchers; Clinical scientists; Leadership team; Product engineers; Clinical stakeholders; Regulatory stakeholders; Product stakeholders

Communication Scope

Translate between teams; Non-technical audiences

Process & Methodology

Agile development methodologies

Full Job Description

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare. Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide. Coronary artery disease is the world's leading cause of death - and we're changing that. Heartflow builds AI that gives clinicians a personalized, precision 3D model of a patient's heart from a single CT scan, helping them diagnose and treat CAD earlier, more accurately, and without invasive procedures. To date, we've helped clinicians manage care for nearly 650,000 patients across more than 1,800 institutions worldwide. Every line of code we ship has a real person on the other side of it. We're looking for a Senior Software Engineer to help lead our agentic AI platform from the inside out. This is a small-team, high-ownership role - you'll be one of a handful of engineers working at the intersection of cutting-edge AI and FDA-regulated medical device software, with direct influence on how Heartflow builds and shi

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