Evotec

drug discovery

SeniorScientistStructuralBiology

Macclesfield, United Kingdom FULL TIME
The Brief

“Senior Scientist Structural Biology at Evotec. Skills: Structural Biology, cryo‑EM, X‑ray crystallography, protein biochemistry, biophysics. establishing and executing Structural Biology work plans. delivery of Structural Biology projects within early drug discovery, across multiple modalities and therapeutic areas”

What You'll Achieve.

delivery of Structural Biology projects; achieve agreed objectives; delivering impactful results

Industry & Context.

drug discovery
Problems you'll solve

scientific problem‑solving; Understanding: Starts conducting more research and recognises threats, trends, and changing can articulate strategic assumptions and riskenefit analysis of situations

Eligibility Requirements

Represent the company at scientific and/or business conferences

What They're Looking For.

Must Have

technical expertise in protein biochemistry, structural biology, and/or biophysics, proven ability to design and deliver results across multiple target families within agreed timelines, budgets, and quality standards, Demonstrated experience leading cryo‑EM and/or X‑ray crystallography projects, from sample preparation through structure refinement, analysis, and delivery, Hands‑on experience operating cryo‑EM instrumentation (e. g. , Titan Krios, Glacios) and/or understanding of synchrotron data collection strategies, Proficiency in processing and analyzing structural data using relevant software packages, such as RELION, cryoSPARC, Phenix, Global Phasing, and/or CCP4, Proven ability to collaborate effectively with computational, biophysical, and medicinal chemistry teams to inform and guide structure‑based drug design, Experience preparing and executing project work plans and building trusted partnerships with internal and external stakeholders, Track record of high‑quality scientific problem‑solving and cross‑functional collaboration, delivering impactful results, Demonstrated research experience with peer‑reviewed publications in a relevant scientific field, relevant first degree combined with several additional years of experience in drug discovery

Nice to Have

some experience in an industrial setting

What You'll Do.

establishing and executing Structural Biology work plans

delivery of Structural Biology projects within early drug discovery

across multiple modalities and therapeutic areas

Design and execute agreed work plans for early drug discovery projects

in alignment with project goals

Support multiple concurrent projects and

direct internal resources to achieve agreed objectives

Review and interpret experimental results to ensure data quality and alignment with project specifications

in partnership with project counterparts

for experimental design

and client presentations

including thorough data analysis prior to release to internal or external customers

Propose experimental designs and novel approaches to identify and advance optimal project strategies

in addition to planning and executing agreed deliverables

Present and publish peer‑reviewed scientific work

and timely data recording and reporting for all laboratory procedures

Oversee routine maintenance and calibration of laboratory instruments to ensure accurate and reliable performance

Adhere to laboratory safety protocols and proactively contribute to improving safety practices

How You'll Work.

Team & Collaboration

collaborate effectively with computational, biophysical, and medicinal chemistry teams; building trusted partnerships with internal and external stakeholders; cross‑functional collaboration; Collaborates with the team and external groups to work towards an established goal

Communication Scope

client presentations; Active Communication: Communicates actively, working on further clarity and responsiveness

Process & Methodology

Design and execute agreed work plans, Support multiple concurrent projects, preparing and executing project work plans, planning and executing agreed deliverables, Occasional Planning: Begins anticipating problems and improves on proactively taking precautions

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