Take Care Of Others

Biotech

SeniorScientist,StemCellModelEngineering

$116–156k Canada FULL TIME
The Brief

“Senior Scientist, Stem Cell Model Engineering at Take Care Of Others. Skills: Stem cell model engineering, CRISPR editing, iPSC models. Develop genetically engineered human iPSC models. Build genetically engineered human iPSC models”

What You'll Achieve.

Support target discovery; Support target validation; Support mechanism-of-action studies

Industry & Context.

Biotech
Problems you'll solve

Troubleshoot complex systems; Identify, troubleshoot, and solve technical and biological failure modes

What They're Looking For.

Must Have

PhD in a related discipline with 2+ years of experience, MSc with 5+ years of experience, BSc with 8+ years of experience

Nice to Have

PhD with 2+ years of postdoctoral and/or industry experience in stem cell biology, molecular biology, cell engineering, genetics, developmental biology, bioengineering, or a related discipline, Demonstrated hands-on experience generating CRISPR edited human iPSC models or other difficult-to-engineer human cellular model systems, experimental judgment in genome-engineering strategy, model design, validation requirements, and interpretation of engineered cell model data, Practical understanding of common failure modes in engineered iPSC models, including clonal artifacts, unintended genetic changes, expression instability, differentiation issues, and loss of engineered behavior, Demonstrated scientific productivity and technical credibility through peer-reviewed publications and patents, communication and collaboration skills and ability to work effectively as part of a multidisciplinary team

What You'll Do.

Develop genetically engineered human iPSC models

Build genetically engineered human iPSC models

Troubleshoot complex systems

Improve current workflows

Drive innovation in human stem cell model engineering

Develop genetically defined iPSC model systems

Define validation strategies

Interpret validation strategies

Identify technical gaps

Build new capabilities

Communicate technical risks

Communicate timelines

Communicate decision points

Communicate model readiness

Maintain high standards for data integrity

Maintain reproducibility

Maintain documentation

Maintain experimental rigor

How You'll Work.

Team & Collaboration

Work effectively as part of a multidisciplinary team

Communication Scope

Communicate technical risks; Communicate timelines; Communicate decision points; Communicate model readiness; Written presentations; Oral presentations; Communication skills

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