Expedition Medicines

biotechnology

SeniorScientist,Proteomics

$126–160k Cambridge, Massachusetts, United States
The Brief

“Senior Scientist, Proteomics at Expedition Medicines. Skills: mass spectrometry-based proteomics, quantitative data analysis, chemoproteomics workflows. Operate, maintain, and troubleshoot LC-MS instrumentation. Develop, optimize, and execute chemoproteomics workflows”

What You'll Achieve.

unlock presently undruggable targets; support drug discovery programs; drive decision-making across multidisciplinary discovery teams; enhance platform capabilities

Industry & Context.

biotechnology
Problems you'll solve

relentless problem solvers; quantitative data analysis skills; biological insight; drive decision-making

What They're Looking For.

Must Have

Ph. D. in analytical chemistry, chemical biology, biochemistry, or a related discipline with 4+ years of industry experience, M. S. degree with 6+ years of industry experience, Extensive hands-on experience with mass spectrometry-based proteomics workflows and instrumentation, Experience with quantitative proteomics methods including TMT, DIA, PRM, or related approaches, Experience with targeted chemoproteomics workflows and applications, Proficiency in analyzing complex, large-scale proteomics datasets using computational methods and programming languages such as Python or R, Expert level understanding of proteomics data analysis software (e.g. MSFragger, ProteomeDiscoverer, Spectronaut, MaxQuant), understanding of experimental design, assay optimization, reproducibility, and quantitative data interpretation

Nice to Have

peptide mapping and/or intact mass spectrometry is preferred, Experience with laboratory automation platforms (e.g. , Hamilton, Agilent Bravo) is a plus

What You'll Do.

and troubleshoot LC-MS instrumentation

and execute chemoproteomics workflows

Design and improve sample preparation workflows

Analyze and interpret proteomics datasets

Collaborate closely with multidisciplinary teams

Develop and implement chemical proteomics technologies

Communicate findings and technical advances

How You'll Work.

Team & Collaboration

Collaborate closely with proteomics, biology, chemistry, and computational teams; Communicate findings and technical advances clearly across cross-functional teams; Excellent cross-functional collaboration skills

Communication Scope

Excellent communication skills

Process & Methodology

manage multiple priorities

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