SeniorScientistI/II-Oncology

**Job Description Summary** The xDC Biotherapeutics group within Oncology Drug Discovery at Novartis Biomedical Research is seeking a highly motivated and collaborative Senior Scientist I/II to advance drug-conjugate discovery programs for the treatment of cancer patients. In this lab-based role, the successful candidate will apply cell and molecular biology techniques to deliver impactful data for target validation and drug optimization efforts. This role requires a strong understanding of and experience with in vitro cell-based assays for drug discovery. This individual will interact collaboratively with colleagues across Biomedical Research and will be a member of multidisciplinary project teams. This is a great opportunity to join a group dedicated to the discovery of biotherapeutics and to support advancement of drug discovery projects into the Novartis portfolio. **Job Description** **Your Key Responsibilities:** * Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager. * Works independently and as a part of a team to design, execute, and analyze in vitro experiments to profile small molecules and biologics and elucidate mechanisms of action * Executes cell and molecular biology assays (e.g. cell titer glo, flow cytometry, JESS, western blot, MSD) * Cultures cells using sterile technique including genetic engineering and validation of cell lines * Uses laboratory automation equipment (liquid handlers, plate readers, dispensers) to perform screens * Maintains an organized and detailed record of all experiments * Works collaboratively across teams and trains other members of team in areas of technical expertise as needed. * Clearly communicates findings and presents research to multidisciplinary project teams * Supports lab operations including management of materials, maintenance of instruments, and general lab duties **Role Requirements:** **Essential Requirements: