Flagship Pioneering, Inc.
Biotech
SeniorScientist,Biology
“Senior Scientist, Biology at Flagship Pioneering, Inc.. Skills: Cell isolation, Cell sorting, SiRNA, Flow cytometry, Microscopy. Design experiments. Execute experiments”
Industry & Context.
Troubleshooting; Data analysis; Experimental design; Statistical analysis
What They're Looking For.
Must Have
Ph.D. in Cell Biology, 6+ years of experience, M.S. degree with substantial industry experience, Expertise in flow cytometry, Cell sorting (FACS), Panel design, Troubleshooting, Data analysis using FlowJo, Hands-on experience with cell isolation, Tissue dissociation, Magnetic bead-based separation, Extensive experience with mouse models, In vitro experimental techniques, SiRNA design, Delivery, Optimization, Functional validation, Hands-on experience with microscopy platforms, Fluorescence, Confocal, Live-cell, High-content imaging systems, Quantitative data analysis, Experimental design, Statistical analysis skills, Excellent communication skills, Presentation skills, Scientific writing skills, Ability to work independently, Ability to work collaboratively
Nice to Have
Experience in translational research, Drug discovery, Preclinical therapeutic development, Experience in biotechnology industry, Pharmaceutical industry settings, Experience with cell profiling, Phenotyping, Functional assays, Primary mouse and human cells, Established cell lines, Experience with single-cell technologies, Spatial biology technologies, ScRNA-seq, CITE-seq, Spatial transcriptomics, Experience managing CROs, External collaborators, Cross-functional project teams, Proficiency with qPCR, Western blotting, ELISA, Multiplex cytokine assays, RNA-seq, Transcriptomic analysis, Gene silencing approaches, Gene-editing approaches, Protein overexpression systems, Immunohistochemistry (IHC), Immunofluorescence (IF), Advanced flow
What You'll Do.
Perform multi-parameter flow cytometry
Design flow cytometry panels
Optimize flow cytometry panels
Troubleshoot flow cytometry
Interpret flow cytometry data
Perform cell isolation
Optimize cell isolation
Execute mouse studies
Characterize phenotypes
Develop siRNA approaches
Apply siRNA approaches
Perform microscopy-based experiments
Analyze imaging datasets
Utilize molecular techniques
Utilize cellular techniques
Support target validation
Support mechanism-of-action studies
Design cell profiling experiments
Analyze cell profiling experiments
Interpret cell profiling experiments
Contribute to biomarker discovery
Contribute to translational research
Contribute to preclinical characterization
Analyze experimental findings
Interpret experimental findings
Generate technical reports
Generate presentations
Generate study summaries
Generate scientific documentation
Collaborate with internal teams
Collaborate with CROs
Collaborate with academic partners
Collaborate with external partners
Mentor junior scientists
Contribute to research environment
Provide scientific leadership
Contribute to research strategy
Lead cross-functional initiatives
Maintain experimental records
How You'll Work.
Team & Collaboration
Cross-functional teams; Senior leadership; Internal teams; CROs; Academic collaborators; External partners; Junior scientists; Research environment
Communication Scope
Presentation; Scientific writing
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