Sanofi
Biopharma
SeniorScientist
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“Senior Scientist at Sanofi. Skills: Protein expression, High-throughput automation, Mammalian expression systems. Lead design, optimization, and implementation of ultra-high-throughput protein and antibody expression platforms. Oversee day-to-day operations of automated systems and robotic platforms”
What You'll Achieve.
Bring next generation, transformative therapies to patients; Support therapeutic candidates designed by state-of-the-art AI/ML models and structural biology; Meet and anticipate growing demand for production of complex protein variants; Drive breakthroughs that could turn the impossible into possible for millions; Deliver compelling growth; Invent medicines and vaccines that treat and protect millions of people; Make drug development quicker and more effective
Industry & Context.
Troubleshooting complex expression challenges; Developing novel solutions
What They're Looking For.
Must Have
Master's degree with minimum 2 years of experience in a research laboratory or a biopharmaiotech company OR Bachelor's degree in biology or related field with minimum 4 years of experience in a research laboratory or a biopharmaiotech company, Extensive experience designing, optimizing, and leading high-throughput automation workflows using advanced liquid handling platforms (Tecan/Hamilton) and integrated robotic systems, Deep expertise in transient mammalian protein and antibody expression, including troubleshooting complex expression challenges, optimization of transfection strategies using recombinant DNA and developing novel solutions, Experience with biological registration and data management systems (e. g. , Genedata Biologics, Spotfire, Pipeline Pilot) and the ability to drive improvements in data integrity and workflow efficiency, Advanced proficiency in Microsoft Excel and the broader Microsoft Office suite, Exceptional organizational, time management, and communication skills, Proven ability to independently lead and manage multiple complex projects simultaneously, Demonstrated experience presenting complex scientific findings to senior leadership, external partners, and broad scientific audiences in a clear, compelling, and strategic manner, Experience contributing to or leading platform development initiatives, technology transfers, or process improvement programs within a pharmaceutical or biotechnology R&D environment
Nice to Have
AI/ML models, structural biology, Antibody Discovery, Protein Production, Protein Engineering
What You'll Do.
and implementation of ultra-high-throughput protein and antibody expression platforms
Oversee day-to-day operations of automated systems and robotic platforms
Drive innovation and scalability of the high-throughput expression platform
Independently manage multiple complex projects simultaneously
Develop and implement data-driven approaches to protein production
Mentor junior scientists
Present complex scientific findings
Identify and evaluate emerging technologies
How You'll Work.
Team & Collaboration
Partner with cross-functional teams (Antibody Discovery, Protein Production, Protein Engineering) to advance LMR initiatives; Align on platform strategies; Influence and align diverse scientific and cross-functional stakeholders
Communication Scope
Communication skills; Present complex scientific findings
Process & Methodology
Independently lead and manage multiple complex projects simultaneously
Full Job Description
**Job title** :_Senior Scientist_ * _Location: Cambridge, MA_ # **About the Job** At Sanofi we are committed in our quest to be a world-class biologics research organization and are steadfast in our goal to bring next generation, transformative therapies to patients. Our global Large Molecule Research (LMR) organization is focused on antibodies and NANOBODY molecules as therapeutic modalities. Our platform enables and partners closely with other research platforms and Sanofi’s therapeutic areas (Immunology & Inflammation, Immuno-Oncology, Rare & Neurologic Diseases) in the discovery and ultimate delivery of new candidate molecules. We are seeking an exceptional and highly motivated Senior Scientist to join our innovative team in the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi's North America R&D LMR organization. The successful candidate will serve as a scientific leader expert in ultra-high-throughput protein and antibody expression, driving the development and optimization of next-generation production platforms that support therapeutic candidates designed by state-of-the-art AI/ML models and structural biology. In addition to overseeing day-to-day operations of cutting-edge automated systems, the candidate will play a pivotal role in shaping the strategic direction of the high-throughput expression platform, identifying opportunities for innovation, and championing cross-functional scientific initiatives across MEST and LMR (Antibody Discovery, Protein Production, and Protein Engineering). The candidate will be expected to independently lead complex projects, mentor junior scientists, and contribute to the broader scientific community through publications, patents, and conference presentations. The demand for production of complex protein variants continues to grow significantly year on year, and this role will be instrumental in designing scalable, forward-looking solutions to meet and anticipate those needs. The ideal candidate b
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