Kailera Therapeutics, Inc.

pharmaceutical or biotech

SeniorScientist,AnalyticalDevelopmentandQualityControl

$143–175k Waltham, Massachusetts, United States Remote Friendly
The Brief

“Senior Scientist, Analytical Development and Quality Control at Kailera Therapeutics, Inc.. Skills: Analytical Development, Quality Control, cGMP Manufacturing, Regulatory Compliance. Support analytical development. Support quality control activities”

What You'll Achieve.

ensure the integrity of data generated by our external partners; ensure compliance with global regulatory standards; support product retest, shelf-life, and expiration dating; generate data to justify specification limits; assess trends in stability data; ensure all analytical activities comply with GMP, ICH guidelines, and other relevant regulations

Industry & Context.

pharmaceutical or biotech
Problems you'll solve

internal and external investigations of quality events (e. g. , deviations, CAPAs, OOS, etc. )

What They're Looking For.

Must Have

PhD with a minimum of 6 years, MS with a minimum of 10 years, or BS with a minimum of 12 years of experience in analytical development and quality control within the pharmaceutical or biotech industry, Proven experience with peptides and small molecules in both injectable and solid oral dosage forms, Experience managing outsourced activities with CDMOs, expertise in analytical techniques such as HPLC, UPLC, MS, GC, and spectroscopic methods, Knowledge of regulatory requirements (FDA, EMA) and ICH guidelines related to analytical development, Proven effective communication and interpersonal skills, Ability to work effectively in a fast-paced, collaborative environment

Nice to Have

Experience with combination drug/device presentations, Experience with establishing peptide drug substance analytical control strategy for various peptide synthesis modalities (linear SPPS, hybrid approaches, LPPS, and/or recombinant)

What You'll Do.

Support analytical development

Support quality control activities

Oversee analytical activities

Perform detailed review

Provide data integrity oversight

Ensure methods are developed

Provide oversight of method validation

Oversee stability programs

Contribute to data summaries

Ensure analytical methods meet requirements

Generate data to justify limits

Assess trends in stability data

Ensure activities comply with regulations

Participate in investigations

Generate cGMP compliant data

Provide technical guidance

Oversee preparation of technical documents

How You'll Work.

Team & Collaboration

Work directly with technical counterparts at vendor sites; Work closely with Manufacturing and Quality Assurance teams; Provide technical guidance and support to internal teams and external partners

Communication Scope

Proven effective communication and interpersonal skills

Process & Methodology

Manage outsourced activities with CDMOs

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