Sanofi

Biopharma

SeniorScientist,AdvancedOcularInVitroModels

$0–0k Cambridge, Massachusetts, United States FULL TIME Remote Friendly
The Brief

“Senior Scientist, Advanced Ocular In Vitro Models at Sanofi. Skills: Ocular in vitro models, iPSC differentiation, Robotics, Drug discovery. Lead scientific initiatives. Design, develop, and validate in vitro ocular models”

What You'll Achieve.

Accelerate drug discovery and development; Deliver transformative treatments; Support Ophthalmology pipeline; Influence project strategies; Advance vision-preserving treatments; Drive breakthroughs; Pipeline progression; Support milestones and decision-making; Make drug development quicker and more effective

Industry & Context.

Biopharma
Problems you'll solve

Independent judgment; Critical thinking; Problem-solving; Decision-making

What They're Looking For.

Must Have

PhD in a relevant scientific discipline, at least 3 years of postdoctoral experience in a pharma or biopharma environment, Expertise in iPSC-based 2D/3D differentiation of ocular cell types for disease modeling and drug discovery, Hands-on experience with robotics, automated cell culture systems, and protocol scaling, Skilled in high-throughput pharmacological and genetic screening using iPSC-derived cells, Proficiency in qPCR, -omics technologies, immunocytochemistry, and advanced imaging and analysis, Demonstrated track record of scientific contributions through publications, patents, or external presentations, Ability to work independently and proactively in ambiguous situations, critical thinking, problem-solving, and decision-making skills, Effective resource planning and time management to meet project objectives

Nice to Have

Experience leading or contributing to drug discovery programs, Experience leading or contributing to ophthalmology drug discovery programs in an industry or translational research setting, Experience and/or deep expertise in ocular disease indications such as age-related macular degeneration (AMD), glaucoma, or other retinal diseases, Experience with CRISPR-based screening approaches for functional genomics and target validation, Proven ability to develop and optimize 3D ocular models (organoids, co-cultures, microphysiological systems), Expertise in automating differentiation protocols for scalability and reproducibility, Demonstrated leadership in research programs relevant to ocular disease, including cross-functional collaboration and strategic planning, Experience developing and validating assays for retinal degeneration, retinal immunology, and neuroinflammation, Experience with computational and statistical analysis tools (e.g., R, Python), Background in bioengineering with emphasis on cellular systems, microfluidics, and translational research

What You'll Do.

Lead scientific initiatives

and validate in vitro ocular models

Lead ophthalmology drug discovery programs

Establish and optimize differentiation protocols

Integrate automation and robotics

Evaluate and implement innovative technologies

Apply models to study disease mechanisms

Develop and validate assays

Deliver scientific presentations

Mentor junior scientists

How You'll Work.

Team & Collaboration

Work proactively across multidisciplinary teams; Cross-functional collaboration

Communication Scope

Excellent communication; Interpersonal skills; Scientific presentations; External publications/presentations

Process & Methodology

Resource planning, Time management, Strategic planning

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