Sanofi
Biopharma
SeniorScientist,AdvancedOcularInVitroModels
Neural analysis suggests this role is
optimal for Senior candidates.
“Senior Scientist, Advanced Ocular In Vitro Models at Sanofi. Skills: iPSC differentiation, Drug discovery programs, Automation and robotics. Lead scientific initiatives. Design advanced ocular models”
Industry & Context.
Problem-solving; Critical thinking
What They're Looking For.
Must Have
PhD in relevant scientific discipline, 3+ years postdoctoral experience, Experience leading drug discovery programs
Nice to Have
Experience leading ophthalmology drug discovery programs, Experience with age-related macular degeneration, Experience with glaucoma, Experience with retinal diseases, Experience with CRISPR-based screening, Ability to develop 3D ocular models, Expertise automating differentiation protocols, Demonstrated leadership in ocular disease research, Experience developing assays for retinal degeneration, Experience developing assays for retinal immunology, Experience developing assays for neuroinflammation, Experience with R, Experience with Python, Background in bioengineering, Emphasis on cellular systems, Emphasis on microfluidics, Emphasis on translational research
What You'll Do.
Lead scientific initiatives
Design advanced ocular models
Develop advanced ocular models
Validate advanced ocular models
Lead ophthalmology drug discovery programs
Contribute to drug discovery programs
Drive target validation
Drive translational strategy
Drive pipeline progression
Establish differentiation protocols
Optimize differentiation protocols
Integrate automation and robotics
Improve reproducibility
Develop automated liquid handling protocols
Implement high-throughput imaging
Implement data acquisition systems
Optimize robotic platforms
Ensure quality control
Standardize automated workflows
Support large-scale screening
Support 3D model generation
Evaluate innovative technologies
Implement innovative technologies
Enhance model complexity
Enhance translational relevance
Apply models to study disease mechanisms
Apply models to validate targets
Apply models to assess therapeutics
Apply models to evaluate safety
Develop assays for retinal degeneration
Develop assays for retinal immunology
Develop assays for neuroinflammation
Validate assays for retinal degeneration
Validate assays for retinal immunology
Validate assays for neuroinflammation
Influence project strategies
Provide scientific expertise
Perform resource planning
Deliver scientific presentations
Provide scientific documentation
Support decision-making
Maintain involvement in professional societies
Mentor junior scientists
Foster scientific excellence
How You'll Work.
Team & Collaboration
Multidisciplinary teams; Cross-functional collaboration
Communication Scope
Scientific presentations; Internal forums; External publications; External presentations
Process & Methodology
Project strategy, Resource planning, Time management
Full Job Description
**Job title** :_Senior Scientist, Advanced Ocular In Vitro Models_ * _Location: Cambridge, MA_ **About the Job** Are you ready to shape the future of ophthalmology research? The race is on to accelerate drug discovery and development to deliver transformative treatments for patients. Your expertise can make a critical impact. Sanofi is seeking a Senior Scientist to lead the development and application of advanced ocular in vitro models supporting our Ophthalmology pipeline. In this role, you will apply deep scientific knowledge and independent judgment to design, implement, and optimize physiologically relevant models for retinal diseases, macular degeneration, glaucoma, and other vision-related indications. You will work proactively across multidisciplinary teams, lead ophthalmology drug discovery programs, influence project strategies, and mentor colleagues while driving innovation in disease modeling and therapeutic evaluation. This position offers the opportunity to contribute strategically to the future of ophthalmology therapeutics and advance vision-preserving treatments worldwide. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. **About Sanofi:** We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. **Main Responsibilities** * Lead scientific initiatives and research project teams to design, develop, and validate advanced in vitro ocular models for early and late-stage ophthalmic research. * Lead and contribute to ophthalmology drug discovery programs, driving target validation, translational strategy, and pipel
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