Crinetics
Healthcare
SeniorScientist1,InVitroPharmacology
“Senior Scientist 1, In Vitro Pharmacology at Crinetics. Skills: GPCR pharmacology, in vitro pharmacology, assay development, data analysis, drug discovery. Engineer and execute in vitro mechanism of action (MoA) and translational studies. Pioneer new technology and assay development initiatives”
Industry & Context.
Outstanding experimental design and problem-solving skills; rigorous approach to complex data analysis
Biology and chemical laboratory environment experience needed., Environmental health and safety requirements also apply., Travel: You may be required to travel for up to 5% of your time., Physical Activities: On a continuous basis, sit at desk for a long period of intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required.
What They're Looking For.
Must Have
Ph.D. in Pharmacology, Biochemistry, Biology, or related discipline with a minimum of 3-5 years of relevant experience., BS or MS degrees must demonstrate a minimum of 11 years of relevant experience., GPCR Specialization: Demonstrated expertise of small molecule GPCR pharmacology, including theoretical understanding of signaling models, mechanisms, and experimental design., Assay Proficiency: Proven technical expertise in developing and executing biochemical, cellular, and radioligand binding assay systems with a focus on high-quality data generation., Scientific Innovation: Ability to leverage existing literature to develop methods, protocols, and technologies that advance pharmacological capabilities., Analytical Excellence: Outstanding experimental design and problem-solving skills, with a rigorous approach to complex data analysis., Adaptability: Proven ability to thrive in a fast-paced, dynamic environment and pivot effectively as program priorities evolve., Communication: Exceptional written and verbal communication skills, with a proven ability to collaborate effectively across multidisciplinary teams., A work ethic characterized by detail-orientation, reliability, and an enthusiasm for both high-level laboratory work and complex data analysis.
What You'll Do.
Engineer and execute in vitro mechanism of action (MoA) and translational studies
Pioneer new technology and assay development initiatives
and execute in vitro pharmacology assays
Evaluate and establish novel in vitro technologies
Perform translational experiments
Engineer and maintain multiple mammalian cell lines in culture
Generate high quality
Ensure meticulous documentation of protocols and results
Critically analyze and interpret complex data
Explore and establish PK/PD relationships
Uphold scientific integrity
Synthesize and effectively communicate findings
Contribute to scientific publications and technical documentation
How You'll Work.
Team & Collaboration
collaborate effectively across multidisciplinary teams; communicate findings to multidisciplinary teams through informal updates, formal presentations, and reports
Communication Scope
Exceptional written and verbal communication skills; effectively communicate findings
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