Roche

Healthcare

SeniorScientificSoftwareEngineer(Fullstack)

Basel, Switzerland FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Senior Scientific Software Engineer (Fullstack) at Roche. Skills: Fullstack development, Scientific data visualization, Workflow design, API design and implementation, Data-intensive application development. Design and build interactive tools for small-molecule drug discovery. Focus on chemical data, molecular design workflows, and model interpretability”

What You'll Achieve.

Deliver more innovative and transformative medicines for patients worldwide; Turning complex data into actionable insights that advance drug discovery and development; Enabling deeper understanding of molecular behavior and the identification of novel therapeutic opportunities; Impact on how scientists design and evaluate small-molecule candidates; Accelerate iteration; Improve how scientists interact with complex datasets; Shared ownership of outcomes and impact

Industry & Context.

Healthcare
Problems you'll solve

Transforming raw data and computational models into meaningful insights remains a key challenge; Bridging the gap between data generation and interpretation; Helping unlock new avenues for scientific discovery and impact; Test hypotheses

What They're Looking For.

Must Have

Ph. D. in an engineering, physical, or quantitative discipline with 2+ years of experience, or a BS/MS with 5+ years of relevant industry experience, Proven track record of designing and building modern web applications across the full stack, Expertise in creating interactive, data-rich visualizations using web-based libraries and technologies, Experience designing and implementing APIs, data services, and application architectures, Proficiency in leveraging modern AI-assisted and agentic coding practices, Ability to work effectively with complex datasets in scientific contexts using Python- or R-based tools, Fluency working with data pipelines, cloud infrastructure, and distributed systems

Nice to Have

Comfortable reasoning about chemical structures and molecular design workflows, including core chemoinformatics concepts (e.g., fingerprints, descriptors, similarity metrics, molecular embeddings), Able to engage productively with medicinal, computational, and machine learning scientists

What You'll Do.

Design and build interactive tools for small-molecule drug discovery

Focus on chemical data

molecular design workflows

and model interpretability

Shape the technical and product direction of platforms

Enable medicinal and computational chemists to explore data

and design better drugs

Design and build end-to-end platforms—spanning front-end interfaces

and data integrations

Enable scientists to run analyses

and interpret model outputs

Lead the development of intuitive

extensible user experiences for complex scientific workflows

Architect and implement APIs

data-intensive applications

Integrate with computational pipelines and machine learning systems

Evaluate and apply emerging technologies

Explore new approaches to scientific data visualization and user interface design

Improve how scientists interact with complex datasets

How You'll Work.

Team & Collaboration

Partnering directly with medicinal chemists, cheminformaticians, and AI scientists; Collaborating across distributed scientific, engineering, and design teams; Taking ideas from early exploration through production-ready applications; Shared ownership of outcomes and impact

Full Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. ### ### The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche. Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. The Analytics and Workflows group within the Center of Excellence (CoE) is dedicated to turning complex data into actionable insights that advance drug discovery and development. We leverage cutting-edge high-throughput technologies and foundational multimodal machine learning models to analyze large-scale chemical and biological data, enabling deeper understanding of molecular behavior and the identification of novel therapeutic opportunities. Despite advances in these fields, however, transforming raw da

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