AstraZeneca
Biopharmaceutical
SeniorResearchScientist–ProteinScientist
“Senior Research Scientist – Protein Scientist at AstraZeneca. Skills: Protein Science, Bioconjugation, Analytical Chemistry, Data Science. Express antibodies. Purify antibodies”
What You'll Achieve.
Deliver proteins to specification; Deliver conjugates to timelines; Improve yield and quality
Industry & Context.
Troubleshooting
What They're Looking For.
Must Have
PhD in Biochemistry, PhD in Structural Biology, PhD in Chemical Biology, Protein expression experience, Protein purification experience, Bioconjugation experience, Analytical techniques experience, Data interpretation experience, Protein biochemistry hands-on experience, Expression systems experience, Purification experience, QC experience, Bioconjugation chemistries ability, Bioconjugation workflows ability, Analytical characterization competence, Troubleshooting competence, Organizational skills, Attention to detail, Manage multiple tasks, High-throughput systems familiarity, Automated purification systems familiarity, Effective communication skills
Nice to Have
Foundation in protein expression, Foundation in protein purification, Foundation in bioconjugation, Structural biology experience, Mechanistic studies experience, Direct bioconjugates experience, Antibody-drug conjugates experience, Antibody-peptide conjugates experience, Complex biologics formats exposure, Developability assessments exposure, AI/ML protein design knowledge, Scripting experience, Data analysis tools experience, Python experience, R experience, Publication contribution experience, Patent contribution experience
What You'll Do.
Characterize antibodies
Express protein constructs
Purify protein constructs
Characterize protein constructs
Perform bioconjugate generation
Execute analytical QC
Ensure data integrity
Support linker-payload development
Support conjugation route development
Prepare protein starting materials
Perform small-scale conjugation
Contribute to functional assays
Maintain electronic lab notebooks
Ensure SOP compliance
Contribute to continuous improvement
Present data at meetings
Contribute to technical reports
Deliver purified proteins
Troubleshoot purification
Troubleshoot conjugation
Apply biophysical characterization
Apply biochemical characterization
Assess protein quality
Assess protein stability
Assess conjugation readiness
Collaborate with scientists
Collaborate with analytical teams
Collaborate with project leads
Ensure workflow integration
Uphold data integrity
Contribute to lab organization
Contribute to process optimization
How You'll Work.
Team & Collaboration
Cross-functional collaboration; Cell biology teams; Biologics profiling teams; Conjugation scientists; Analytical teams; Project leads
Communication Scope
Data presentation
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