SeniorResearchAssociate,PlatformBiology

## Description About Us Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.   Opportunity The Senior/Principal Research Associate will join our Platform Biology team and will be a key player in driving our cutting-edge AI RNA therapeutics discovery platform. In this role, you will support novel target validation by utilizing a variety of genome engineering approaches in both pooled and arrayed formats. The ideal candidate will have strong gene editing, cell biology and molecular biology experience in an industrial setting. Prior experience with oligonucleotide therapeutics such as ADAR, ASO, and/or siRNAs is also highly beneficial. The successful candidate should demonstrate initiative and be able to thrive in a dynamic work environment with cross-functional teams working together to achieve company goals. *Title will be commensurate with prior experience. This position is onsite at our Cambridge, MA site.   ## Key Responsibilities Plan and execute genome engineering experiments to generate models for target validation. Execute barcoded pooled screening assays, including NGS library preparation. Support the development of novel biochemical, cellular and functional assays for our internal therapeutic pipeline. Maintain and transfect a variety of mammalian cell lines, such as immortalized cell lines. Perform standard molecular biology techniques (e.g. PCR, qPCR, molecular cloning, etc.). Collaborate with a cross-functional team in a dynamic, matrixed environment to achieve shared company deadlines. Clearly document experiments, standard operating pro