Lila Sciences
Biotechnology
SeniorResearchAssociate
Neural analysis suggests this role is
optimal for Senior candidates.
“Senior Research Associate at Lila Sciences. Skills: Antibody display, Biologic development, NGS data analysis, Assay development. Support development of display workflows. Determine binding of antibodies”
Industry & Context.
Root cause analysis
What They're Looking For.
Must Have
MSc in Molecular Biology or Biotechnology, 1+ year experience developing antibodies or peptides, BSc with 3+ years experience developing antibodies or peptides, Expertise using pooled display assays, Experience selecting antibodies using yeast or in vitro display, Experience culturing yeast, bacteria, or phage, Experience expressing proteins for display, Experience with molecular biology techniques, Experience with magnetic bead-based purification, Experience with flow cytometry, Experience with sorting yeast using FACS, Experience with novel assay development, Experience with analysis of NGS sequencing data
Nice to Have
Experience operating Illumina sequencers, Experience with automation, Experience with single cell sequencing, Experience with in situ sequencing
What You'll Do.
Support development of display workflows
Determine binding of antibodies
Determine stability of antibodies
Determine function of antibodies
Determine binding of biologics
Determine stability of biologics
Determine function of biologics
Generate high-dimensional datasets
Improve assay precision
Improve assay reliability
Collaborate with synthetic biologists
Collaborate with automation engineers
Make assays automation-ready
Partner with protein design teams
Partner with nucleic acid teams
Partner with protein teams
Partner with automation teams
Create libraries of protein designs
Utilize MACS for selection
Utilize FACS for selection
Design platforms for experimentation
Exercise platforms for experimentation
Design automated experimentation
Design high-throughput experimentation
Design data-rich workflows
Refine best practices
How You'll Work.
Team & Collaboration
Synthetic biologists; Automation engineers; Cell biology teams; Protein design teams; Nucleic acid teams; Data scientists
Full Job Description
Your Impact at LILA We're hiring a Senior Research Associate to support development and execution of display workflows to determine the binding, stability, and function of antibodies and other biologics. The role will develop and execute assays to generate highly multiplexed, high-dimensional datasets, and will continually optimize those assays to improve precision, scope, reliability, and speed. You will collaborate with synthetic biologists, automation engineers, and others to make these assays automation-ready. This role partners across cell biology, protein design, and nucleic acid teams to support biologic development programs and the development of scientific super intelligence. What You'll Be Building Support development of in vitro and in vivo display workflows to determine the binding, stability, and function of antibodies and other biologics. Implement display workflows to support antibody and biologic development programs and to generate novel high-dimensional datasets that advance scientific super intelligence. Partner with protein design, nucleic acid, protein, and automation teams to create highly precise and complex libraries of protein designs. Utilize MACS and FACS for the selection of biologics with desired properties. Closed-loop experimentation and execution: partner closely with engineering and automation to design and exercise platforms for automated, high-throughput experimentation and data-rich workflows. Collaborate, lead, and communicate: work with cell biologists, synthetic biologists, automation engineers, protein design scientists, and data scientists to document systems, share insights, and refine best practices in autonomous science. What You'll Need to Succeed MSc in Molecular Biology, Biotechnology, or a related field with 1+ year of experience, or BSc with 3+ years, developing antibodies or peptides using display-based methods (in vitro or yeast display). Expertise using pooled display assays in antibody development. Experience sele
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