CRB
Engineering
SeniorProcessEngineer-SmallMolecule/Oligo/Peptide
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“Senior Process Engineer- Small Molecule/ Oligo/ Peptide at CRB”
Industry & Context.
Full Job Description
CRB is a leading provider of sustainable engineering, architecture, construction and consulting solutions to the global life sciences and food and beverage industries. Our more than 1,100 employees provide best-in-class solutions that drive success and positive change for our clients, our people and our communities. CRB is a privately held company with a rich history of serving clients throughout the world, consistently striving for the highest standard of technical knowledge, creativity and execution. We are seeking a skilled and experienced Process Engineer III/ IV or V with deep expertise in small molecule manufacturing to join our engineering consulting team. This role combines technical leadership with strategic client engagement, supporting process design, scale-up, optimization, and regulatory compliance across a variety of pharmaceutical and chemical industry projects. The Process Engineer III will lead the design and execution of process scopes—such as unit operations, systems, or facility areas—on small to medium-sized projects. You will manage scope, budget, and schedule, while maintaining clear communication with clients and internal teams. This role also includes mentoring junior staff, contributing to high-quality deliverables, and supporting capital project planning and regulatory alignment. This position can be based near any CRB location, remote option will be considered Key Responsibilities * Lead and support client projects focused on small molecule API process development, scale-up, and manufacturing optimization. * Conduct site assessments, gap analyses, and provide recommendations for process improvements and compliance. * Develop process flow diagrams (PFDs), piping and instrumentation diagrams (P&IDs), and mass/energy balances. * Translate client requirements into actionable design scope and document decisions, open issues, and action items. * Identify and escalate scope changes or design deviations to project leadership. * Collaborate with c
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