Orchard Therapeutics

Gene Therapy

SeniorDirector,FacilitiesEngineering

£150–220k ~AI est. London, England, United Kingdom FULL TIME
The Brief

“Senior Director, Facilities Engineering at Orchard Therapeutics. Skills: GMP manufacturing suite, Facilities engineering, Project leadership. Lead end-to-end design and construction. Partner with architects and contractors”

Industry & Context.

Gene Therapy
Problems you'll solve

Problem-solving

What They're Looking For.

Must Have

Degree in Engineering, Life Sciences, or related, Experience managing facilities budgets, Experience managing multiple workstreams, Experience managing external contractors, Technical knowledge of GMP engineering systems, Understanding of UK/EU health, safety, and environmental legislation, In-depth knowledge of GMP regulatory frameworks, Working knowledge of sterility assurance principles

Nice to Have

Relevant professional qualifications (CIBSE, IWFM, IChemE)

What You'll Do.

Lead end-to-end design and construction

Partner with architects and contractors

Oversee development of engineering deliverables

Ensure facility design meets regulatory requirements

Manage installation and commissioning of systems

Oversee contractor qualification and performance

Lead installation and commissioning into operation

Provide engineering leadership to strategy

Establish and own maintenance program

Ensure continuous facility compliance

Maintain facility-related SOPs

Serve as primary contact for inspections

Own engineering response to excursions

Develop and oversee continuous improvement

Provide senior oversight for operations

Set strategic framework for compliance

Own strategic vendor relationships

Lead capital projects for spaces

Ensure integration between programmes

Line manage and develop team

Conduct performance reviews

Support professional development

Manage facilities and engineering budget

Represent function at leadership level

Champion continuous improvement initiatives

How You'll Work.

Team & Collaboration

Partner with architects; Partner with contractors; Collaborate with QA; Work with Quality Assurance; Work with Manufacturing; Work with programme management; Work through Managers; Collaborate with stakeholders

Communication Scope

Convey technical information

Process & Methodology

Project management, Managing workstreams, Managing contractors

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