Pfizer
Pharmaceutical
SeniorDirector,AppliedAI
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“Senior Director, Applied AI at Pfizer. Skills: Applied AI, System architecture, Enterprise strategy, AI governance. Shape and evolve enterprise or domain-level AI strategy. Connect AI initiatives to measurable impact”
What You'll Achieve.
Connect AI initiatives to measurable impact; Ensure AI investments translate into enterprise-wide value; Ensure AI investments produce reusable capabilities; Ensure AI investments produce unified direction
Industry & Context.
System thinking; Technical judgment
Permanent work authorization
What They're Looking For.
Must Have
12+ years in AI, data, or software architecture, Significant experience at enterprise or multi-domain scale, Shape enterprise or domain-level strategy and architecture direction, Tie strategy to measurable business outcomes, Current hands-on technical proficiency, Read, write, build, and review code, Experience leading full-time engineers, contractors, and vendor partners, Deliver production-grade systems, Experience in operating-model design, Experience in governance frameworks, Experience in architectural decision frameworks, Permanent work authorization in the United States
Nice to Have
Hands-on depth to lead the build
What You'll Do.
Shape and evolve enterprise or domain-level AI strategy, Connect AI initiatives to measurable impact, Influence leadership on AI application, Reshape processes and operating models, Design and evolve enterprise AI operating models, Design target technology landscape, Design relationships between platforms, capabilities, and solutions, Create decision frameworks, Create architectural principles, Drive portfolio-level architectural decisions, Balance value vs.
cost, Balance speed vs.
governance, Balance standardization vs.
flexibility, Balance innovation vs.
reliability, Steer toward enterprise reuse, Prevent duplication, Define and steward AI architecture standards, Define and steward solution design standards, Define and steward operational execution standards, Prevent fragmentation, Prevent architectural drift, Prevent systemic technical debt, Stay hands-on where it matters, Validate emerging technology, De-risk decisions, Lead from the front on hardest problems, Lead a mixed team, Scope vendor work, Direct vendor work, Set quality standards, Set security standards, Manage vendor performance, Manage vendor spend, Ensure critical capability stays with Pfizer, Ensure critical IP stays with Pfizer, Mentor Directors, Mentor engineers, Raise the technical bar, Assess emerging technologies, Assess vendor landscape, Assess industry trends, Assess research, Translate signal into enterprise implications, Distinguish hype from viable solutions, Act as internal thought leader, Act as external thought leader.
How You'll Work.
Team & Collaboration
Lead mixed team; Work through strategic influence; Direct engineers, contractors, vendors
Communication Scope
Influence senior executives; Guide technical leaders
Process & Methodology
Portfolio management, Trade-off leadership
Full Job Description
_**ROLE SUMMARY**_ The Senior Director, Applied AI is a system-level AI and architecture leader who shapes enterprise and domain-level direction by connecting technological possibility to business value, operating-model design, and measurable outcomes. You determine what should be built and why it matters, how it should be governed, and how to keep solutions coherent at scale — working through strategic influence, architectural direction, standards, and decision frameworks. You are also a builder. You stay close enough to the technology to keep your judgment credible — architecting and reviewing the hardest technical decisions, and setting the engineering bar others meet. And you lead a mixed team of full-time engineers, contractors, and vendor partners whose work you scope, direct, and hold to Pfizer's quality and security standards. As part of Pfizer's commercial AI organization, you help deliver on Pfizer's ambition to be the most AI-forward company — ensuring AI investments translate into coherent, enterprise-wide value rather than disconnected local solutions. **Why This Role Matters** Pfizer's purpose — breakthroughs that change patients' lives — has always depended on the company's willingness to transform how it works, not only what it discovers. Being the most AI-forward company, and reinventing how we work from end to end, is the next chapter in that story. Realizing that ambition depends on doing AI coherently and at scale, not as a set of disconnected efforts. This role ensures the organization builds AI that is sound, reusable, and aligned — preventing fragmentation and technical debt while staying technical enough to know whether what is proposed is actually buildable. You are responsible for ensuring AI investments produce real outcomes, reusable capabilities, and a unified direction. **Candidate Profile** You are a system thinker and transformation shaper, comfortable under ambiguity and at enterprise scale, who has kept your hands on the technology.
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