Novartis
Healthcare
ScientistUpstreamCellCulture
“Scientist - Upstream Cell Culture at Novartis. Skills: Cell culture, Gene therapy, Process development, AAV & LVV. Lead and support activity with cross-functional organizations. Plan, execute, and document experiments”
Industry & Context.
Troubleshoot process and equipment; Data-driven decisions
Must be accessible for Durham, NC location, Required to be in Durham, NC office 5x/week
What They're Looking For.
Must Have
Bachelor's in biochemistry, chemical engineering, bioengineering, or related technical field with 4-6 years relevant experience or Master's with 2-4 or PhD with 0-2, Extensive experience with production of virus or biologics from mammalian expression systems, Hands on experience with different cell lines, bioreactors, and scale-down model, Organized and systematic approach to viral or biologic production, Ability to multi-task and meet tight timelines, Knowledge with a variety of biopharmaceutical purification processes, Proficient in statistical analysis principles and approaches, Working knowledge and experience with Design of Experiment (DoE), Ability to analyze data to make date-driven decisions, Innovative with a continuous improvement mindset, Excellent team player with good communication skills
Nice to Have
Knowledge of viral cell/gene therapy, Previous experience with AAV & LVV processes development
What You'll Do.
Lead and support activity with cross-functional organizations
and document experiments
Define the process and method of delivery
Design and execution of time-sensitive experiments
Capture related data and knowledge
Advance development products from Research to Development to
Maintain awareness of novel biochemical and biophysical technologies
Keep up to date with scientific literature
Apply understanding of regulatory expectations
Contribute to process risk assessments
Justify development strategies and experiment designs
Design and apply DOE and QbD studies
optimize and characterize cell culture and
Execute experiments and troubleshoot process and equipment
Conduct laboratory studies to enhance gene therapy manufacturing
Support initiatives for new technology development
Support continuous improvement projects
Provide support for process
and characterization knowledge
Track records of collaborative relations
Ensure all documentation and reports are accurate
Write detailed experimental protocols
Develop Bill of Materials (BOM)
Execute and document experimental studies
Review and report data
Create and revise SOPs for equipment and process
Lead the authoring of technical reports
Lead the authoring of CMC sections for regulatory
How You'll Work.
Team & Collaboration
Cross-functional organizations; Research and development; Analytical development; Pilot scale operations
Applying for this Scientist - Upstream Cell Culture role?
Most applicants get filtered before a human reads their resume. See if yours makes the cut.
How to Apply on Workday
- Workday has a multi-step form — save your progress after every section.
- "Apply With LinkedIn" can fail or lose data; manual entry is more reliable.
- Watch for the "Submit for Review" final step — hitting "Save" alone does not submit.
- Job requisition numbers are useful when following up with HR by email.
ANONYMOUS · UNFILTERED
What do employees actually say about Novartis?
Real rants from real employees. Read before you apply.