Superluminal Medicines, Inc.
Scientist-PrincipalScientist,ProteinDesign&Structure
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optimal for Principal Scientist candidates.
“Scientist-Principal Scientist, Protein Design & Structure at Superluminal Medicines, Inc.”
What They're Looking For.
Must Have
Subject matter expert in membrane protein biochemistry, Develop and implement strategies to express GPCRs, Develop and implement strategies to purify GPCRs, Develop and implement strategies to characterize GPCRs, Deep knowledge of GPCR biology, Deep knowledge of membrane protein structure-function relationships, Proven expertise in molecular biology, Hands-on experience in protein purification of GPCRs, Familiarity with protein stabilization techniques
Nice to Have
Experience with structural biology methods, Experience in laboratory automation
Full Job Description
About Superluminal Medicines: Superluminal Medicines is a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure. We are expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation. Position Summary We are seeking a highly innovative and experienced Scientist/Senior Scientist/Principal Scientist to lead GPCR protein engineering and production efforts. The successful candidate will be a subject matter expert (SME) in membrane protein biochemistry, responsible for developing and implementing strategies to express, purify, and characterize challenging G-protein coupled receptors (GPCRs) to support structural biology, biophysics, and drug discovery programs. This role involves hands-on laboratory work and scientific leadership. Key Responsibilities Protein Engineering Strategy: Design, execute, and optimize constructs for GPCR expression. Expression evaluate and implement new technologies. Scientific Documentation or a master’s or bachelor’s degree in a related field with commensurate industry experience. Deep knowledge of GPCR biology and membrane protein structure-function relationships. Proven expertise in molecular biology (cloning, construct design, mutagenesis). Hands-on experience in protein purification of GPCRs using FPLC (affinity, SEC). Familiarity with protein stabilization techniques (e.g., antibody fragments, fusion partners, mutagenesis). Excellent communication, interpersonal, and leadership skills. Preferred Qualifications Experience with structural biology methods (data collection and processing for Cryo-EM). Experience in laboratory automation in protein sciences color; creed; religion; nat
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