Legend Biotech

biotechnology

Scientist,ExploratoryTechnologyinvivoCART

Philadelphia, Pennsylvania, United States
The Brief

“Scientist, Exploratory Technology in vivo CAR-T at Legend Biotech. Skills: immunology, cell therapy, gene therapy, in vivo CAR T cell platform development. Produce research grade lentivirus to perform exploratory research. Perform lentivirus titering such as p24 ELISA and qPCR”

What You'll Achieve.

Deliver reliable and consistent data

Industry & Context.

biotechnology
Problems you'll solve

problem-solving skills

What They're Looking For.

Must Have

PhD in Immunology, Cell Biology, Molecular Biology, or a related field OR Master’s degree with 3–6+ years of relevant experience, Hands-on experience in immunology, cell therapy, gene therapy, or related fields, Cell biology and molecular biology techniques, Virology and viral vector systems (e. g. , lentivirus), Mammalian cell culture and immune cell handling, Flow cytometry and immunoassays, data analysis, organization, and problem-solving skills, Ability to work both independently and collaboratively

Nice to Have

Experience with viral vector systems (especially lentivirus) is highly preferred, Industry or postdoctoral experience is a plus, Experience to support project from early research to clinical stage is a plus

What You'll Do.

Produce research grade lentivirus to perform exploratory research, Perform lentivirus titering such as p24 ELISA and qPCR, Contribute in developing and optimizing novel cell and gene therapy platforms and in vitro cell-based immunoassays such as whole blood transduction, Setup in vitro CAR T cell culture, characterization and functional assays including PBMC culture, T cell isolation and expansion, multi-color flow cytometry, cytotoxic assays (e.

IncuCyte), cytokine detection (e.

MSD) and VCN analysis, Independently design and execute experiments, Support laboratory chores.

How You'll Work.

Team & Collaboration

work closely with the team and cross-functional teams in a highly collaborative environment; present the data within research team and cross-functional teams

Communication Scope

present the data within research team and cross-functional teams

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