Element Biosciences

Healthcare

Scientist,Chemistry

$116–149k san diego, california, united states FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Mid candidates.

The Brief

“Scientist, Chemistry at Element Biosciences. Skills: Synthesis of fluorescent dyes, Purification of fluorescent dyes, Characterization of fluorescent dyes, NMR, LCMS, Excitation/emission spectra. Responsible for the synthesis and purification of fluorescent dyes, NHS esters, dye conjugates and energy transfer dyes. Responsible for the synthesis and purification of nucleosides, nucleotides and reversible terminators”

What You'll Achieve.

Empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity

Industry & Context.

Healthcare
Eligibility Requirements

Frequently moves boxes weighing up to 20 pounds, Physical activity and the handling of chemicals, Follow the safety protocols, Familiar with personal protective equipment (PPE) while working in the laboratory environment, Up to 5% travel or as needed

What They're Looking For.

Must Have

B. S. in chemistry, biochemistry or related field., Minimum 5 years’ experience with synthesis and HPLC purification (reverse phase and ion exchange) of small molecules, fluorescent dyes, dye conjugates, energy transfer dyes, nucleosides and nucleotides, Must have experience characterizing fluorescent dyes, dye conjugates, energy transfer dyes, nucleosides and nucleotides by NMR (1H, 31P, 19F, DEPTQ, HMBC, HSQC), LCMS, and excitationission spectra, Must be a good lab citizen and work collaboratively with others, Must have experience with SciFinder, ChemDraw and Mnova, Experience with NMR, LCMS and excitationission spectra is a must

Nice to Have

Advanced degree is a plus, Experience in bioconjugation, assay development, photo(redox)chemistry, system integration is a plus

What You'll Do.

Responsible for the synthesis and purification of fluorescent dyes

dye conjugates and energy transfer dyes

Responsible for the synthesis and purification of nucleosides

nucleotides and reversible terminators

Responsible for the synthesis and purification of water-soluble spacers and cleavable linkers

Proactively seek out new information in the literature and incorporate it into individual projects

How You'll Work.

Team & Collaboration

Collaborate cross-functionally to support R&D needs and provide assistance to other departments; Work collaboratively with others

Full Job Description

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness. We are seeking an experienced Scientist, Chemistry who will play a pivotal role in inventing new reagents for next generation DNA sequencing. This is an incredible opportunity for someone who is passionate about the discovery of new fluorescent dyes. We are looking for candidates with a solid background in the synthesis and purification of fluorescent dyes and conjugates. Experience with NMR, LCMS and excitation/emission spectra is a must. This role will report directly to the Head of Chemistry. If you possess the following and want to make a meaningful impact, we invite you to explore this role. Essential Functions and Responsibilities: Responsible for the synthesis and purification of fluorescent dyes, NHS esters, dye conjugates and energy transfer dyes Responsible for the synthesis and purification of nucleosides, nucleotides and reversible terminators Responsible for the synthesis and purification of water-soluble spacers and cleavable linkers Proactively seek out new information in the literature and incorporate it into individual projects Collaborate cross-functionally to support R&D needs and provide assistance to other departments Education and Experience: B. S. in chemistry, biochemistry or related field. Advanced degree is a plus Minimum 5 years’ experience with synthesis and HPLC purification (reverse phase and ion exchange) of small molecules, fluorescent dyes, dye conjugates, energy transfer dyes, nucleosides and nucleotides Must have experience characterizing fluorescent dyes, dye conjugates, energy transfer dyes, nucleosides and nucleoti

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