Acerta Pharma

Biotechnology

Scientist,BioscienceCell&MechanisticBiology

Nijmegen, Netherlands FULL TIME
The Brief

“Scientist, Bioscience – Cell & Mechanistic Biology at Acerta Pharma. Skills: Flow cytometry, Cell-based assays, Mechanistic studies, Haematology-oncology. Design and execute cell-based assays. Drive DMTA cycle”

What You'll Achieve.

Transforming the lives of patients with haematological cancers; Help advance innovative therapies for patients with haematological cancers; Contribute to cutting-edge oncology research; Help shape the future of oncology drug discovery; Develop novel therapies for haematological malignancies; Drive the design-make-test-analyze (DMTA) cycle; Uncover compound mechanisms of action and pathway biology; Translate findings into clear scientific recommendations; Develop innovative treatments for patients with cancer

Industry & Context.

Biotechnology
Problems you'll solve

Critical thinking; Scientific reasoning skills

Eligibility Requirements

Currently living and working within the EU, Preferably in possession of an EU passport, Willing to work onsite in Oss until the move to Amsterdam UMC in early 2027, Relocation support is unfortunately not available

What They're Looking For.

Must Have

MSc in Molecular Biology, Cell Biology, Cancer Biology, Pharmacology, or a related field, or a relevant Bachelor/HBO degree with 5+ years of industry experience in drug discovery and cell biology, Experience within biotech or pharma environments supporting DMTA-driven discovery programs, Hands-on expertise in flow cytometry, cellular assay development, and biological data analysis, Experience with general cell and mol bio techniques (tissue culture, western, qPCR), Scientific reasoning skills, Structured way of working, Excellent collaboration and communication skills, Fluency in English

Nice to Have

3–5 years of advanced flow cytometry experience in complex biological systems, Experience with high-parameter panel design, compensation strategies, and cell sorting, Experience with haematology-oncology models, primary patient samples, or 3D/spheroid systems, Familiarity with major cytometry platforms (e.g. BD systems), including troubleshooting and maintenance, Expertise in CRISPR/Cas9, RNAi, cloning, qPCR, Western blotting, ELISA/HTRF, or reporter assays, Hands-on experience with AML, CLL, MM, or related haematological models, Experience working with primary patient samples and human materials under ethical and biosafety frameworks, Experience with 3D/spheroid cultures and live-cell imaging platforms such as Incucyte

What You'll Do.

Design and execute cell-based assays

Lead mechanistic studies

Uncover compound mechanisms

Investigate pathway biology

Develop and optimise flow cytometry assays

Design and validate cell-based assays

Perform mechanistic studies

Work with haematology-oncology disease models

Apply molecular biology techniques

Analyse and interpret biological datasets

Translate findings into recommendations

Maintain ELN documentation

Present results to teams

Support collaboration

Guide junior scientists

How You'll Work.

Team & Collaboration

Support collaboration, knowledge sharing, and guidance of junior scientists where appropriate; Present results to multidisciplinary project teams; Work closely with colleagues in the US, Canada, Spain and the UK

Communication Scope

Excellent communication skills

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