Acerta Pharma
Biotechnology
Scientist,Bioscience–Cell&MechanisticBiology
Neural analysis suggests this role is
optimal for Mid candidates.
“Scientist, Bioscience – Cell & Mechanistic Biology at Acerta Pharma. Skills: Flow cytometry, Cell-based assays, Mechanistic studies, Haematology-oncology. Design and execute cell-based assays. Drive DMTA cycle”
What You'll Achieve.
Transforming the lives of patients with haematological cancers; Help advance innovative therapies for patients with haematological cancers; Contribute to cutting-edge oncology research; Help shape the future of oncology drug discovery; Develop novel therapies for haematological malignancies; Drive the design-make-test-analyze (DMTA) cycle; Uncover compound mechanisms of action and pathway biology; Translate findings into clear scientific recommendations; Develop innovative treatments for patients with cancer
Industry & Context.
Critical thinking; Scientific reasoning skills
Currently living and working within the EU, Preferably in possession of an EU passport, Willing to work onsite in Oss until the move to Amsterdam UMC in early 2027, Relocation support is unfortunately not available
What They're Looking For.
Must Have
MSc in Molecular Biology, Cell Biology, Cancer Biology, Pharmacology, or a related field, or a relevant Bachelor/HBO degree with 5+ years of industry experience in drug discovery and cell biology, Experience within biotech or pharma environments supporting DMTA-driven discovery programs, Hands-on expertise in flow cytometry, cellular assay development, and biological data analysis, Experience with general cell and mol bio techniques (tissue culture, western, qPCR), Scientific reasoning skills, Structured way of working, Excellent collaboration and communication skills, Fluency in English
Nice to Have
3–5 years of advanced flow cytometry experience in complex biological systems, Experience with high-parameter panel design, compensation strategies, and cell sorting, Experience with haematology-oncology models, primary patient samples, or 3D/spheroid systems, Familiarity with major cytometry platforms (e.g. BD systems), including troubleshooting and maintenance, Expertise in CRISPR/Cas9, RNAi, cloning, qPCR, Western blotting, ELISA/HTRF, or reporter assays, Hands-on experience with AML, CLL, MM, or related haematological models, Experience working with primary patient samples and human materials under ethical and biosafety frameworks, Experience with 3D/spheroid cultures and live-cell imaging platforms such as Incucyte
What You'll Do.
Design and execute cell-based assays
Lead mechanistic studies
Uncover compound mechanisms
Investigate pathway biology
Develop and optimise flow cytometry assays
Design and validate cell-based assays
Perform mechanistic studies
Work with haematology-oncology disease models
Apply molecular biology techniques
Analyse and interpret biological datasets
Translate findings into recommendations
Maintain ELN documentation
Present results to teams
Support collaboration
Guide junior scientists
How You'll Work.
Team & Collaboration
Support collaboration, knowledge sharing, and guidance of junior scientists where appropriate; Present results to multidisciplinary project teams; Work closely with colleagues in the US, Canada, Spain and the UK
Communication Scope
Excellent communication skills
Full Job Description
Driven by science and collaboration, you will help advance innovative therapies for patients with haematological cancers. Join Acerta Pharma, part of AstraZeneca, and contribute to cutting-edge oncology research in an international environment where your expertise and ideas are valued. **Scientist, Bioscience – Cell & Mechanistic Biology** (Haematology Oncology / Small Molecules) **Location: Pivot Park Oss - > Amsterdam UMC Campus (from early 2027) Full time | 40 hours per week** At Acerta Pharma, part of the AstraZeneca group, we are driven by one mission: transforming the lives of patients with haematological cancers through groundbreaking science and innovative therapies. As we expand our research footprint in the Netherlands, we are building toward an exciting new chapter — the launch of the AstraZeneca Netherlands R&D hub in Amsterdam in early 2027. Until then, you will work from our state-of-the-art facilities in Oss before transitioning to our new Amsterdam UMC campus location. This is a unique opportunity to join a growing oncology research organisation at a pivotal moment and help shape the future of oncology drug discovery, developing novel therapies for haematological malignancies. **The role** As a Scientist in Bioscience, with expertise in cell and molecular biology, you will support haematology-oncology drug discovery programs across our Oss and future Amsterdam sites. You will design and execute innovative cell-based assays that drive the design-make-test-analyze (DMTA) cycle, while leading mechanistic studies to uncover compound mechanisms of action and pathway biology. We are particularly interested in candidates with strong hands-on expertise in flow cytometry, including multicolor panel design, assay development, and high-dimensional data analysis. The ideal candidate combines excellent laboratory skills with scientific curiosity, critical thinking, and a passion for translating complex biological data into meaningful insights. Experience in haema
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