ORIC Pharmaceuticals
Biotech
ResearchAssociateII-Formulation(Contract)
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“Research Associate II - Formulation (Contract) at ORIC Pharmaceuticals. Skills: Formulation development, Sterile injectables, Aseptic processing, GMP manufacturing. Develop and optimize formulations for small molecule and. Develop and optimize sterile injectable formulations”
What You'll Achieve.
Successfully develop and scale up drug product formulations; Ensure product quality and compliance with GMP standards; Support timely regulatory submissions
Industry & Context.
Troubleshooting; Root cause analysis; Data analysis
What They're Looking For.
Must Have
5+ years of experience in formulation development, BS/MS in Chemistry, Chemical Engineering, or related field, Experience with small molecule drug product development, Experience with sterile injectable formulation development, Experience with aseptic processing, Experience with GMP manufacturing, Experience with analytical method development and validation
Nice to Have
PhD in Chemistry, Chemical Engineering, or related field, Experience with biologics formulation development, Experience with lyophilization cycle development, Experience with parenteral drug delivery systems, Experience with regulatory submissions (IND, NDA)
What You'll Do.
Develop and optimize formulations for small molecule and
Develop and optimize sterile injectable formulations
Develop and optimize aseptic processing methods
Perform analytical testing to characterize drug products
Develop and validate analytical methods
Support GMP manufacturing activities
Troubleshoot formulation and manufacturing issues
Document experimental results and prepare reports
Collaborate with cross-functional teams
Contribute to regulatory submissions
How You'll Work.
Team & Collaboration
Cross-functional teams; Research and Development; Manufacturing; Quality Assurance
Communication Scope
Technical reporting; Presentation skills
Process & Methodology
Project planning, Timeline management
Full Job Description
ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com, and follow us on X or LinkedIn. We are seeking a highly skilled Contract Research Associate II with expertise in formulation to join ORIC’s formulation and drug delivery team. The successful candidate will support ORIC’s early and late-stage drug product development activities including preclinical formulation, pre-formulation and drug product analytical testing to support solid oral dose development. This person is hands-on in the laboratory and will be responsible for data collection and analysis and will present their work regularly at team meetings. The ideal candidate will be self-driven, highly organized, focused and enjoy working in a dynamic team environment. Responsibilities include and are not limited to the following: * Collaborate with Research to identify and prepare preclinical formulations. Perform supportive stability studies and develop instructions to enable reproducible formulation preparation. * Design and execution of pre-formulation studies to determine the chemical and physical properties of our small molecule drug candidates. * Analytical support for our drug products which include in-process testing of powder blends and final product testing of tablets. ## Qualification
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