ORIC Pharmaceuticals

Biotech

ResearchAssociateII-Formulation(Contract)

$0–0k South San Francisco, California, United States CONTRACT
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for entry candidates.

The Brief

“Research Associate II - Formulation (Contract) at ORIC Pharmaceuticals. Skills: Formulation development, Sterile injectables, Aseptic processing, GMP manufacturing. Develop and optimize formulations for small molecule and. Develop and optimize sterile injectable formulations”

What You'll Achieve.

Successfully develop and scale up drug product formulations; Ensure product quality and compliance with GMP standards; Support timely regulatory submissions

Industry & Context.

Biotech
Problems you'll solve

Troubleshooting; Root cause analysis; Data analysis

What They're Looking For.

Must Have

5+ years of experience in formulation development, BS/MS in Chemistry, Chemical Engineering, or related field, Experience with small molecule drug product development, Experience with sterile injectable formulation development, Experience with aseptic processing, Experience with GMP manufacturing, Experience with analytical method development and validation

Nice to Have

PhD in Chemistry, Chemical Engineering, or related field, Experience with biologics formulation development, Experience with lyophilization cycle development, Experience with parenteral drug delivery systems, Experience with regulatory submissions (IND, NDA)

What You'll Do.

Develop and optimize formulations for small molecule and

Develop and optimize sterile injectable formulations

Develop and optimize aseptic processing methods

Perform analytical testing to characterize drug products

Develop and validate analytical methods

Support GMP manufacturing activities

Troubleshoot formulation and manufacturing issues

Document experimental results and prepare reports

Collaborate with cross-functional teams

Contribute to regulatory submissions

How You'll Work.

Team & Collaboration

Cross-functional teams; Research and Development; Manufacturing; Quality Assurance

Communication Scope

Technical reporting; Presentation skills

Process & Methodology

Project planning, Timeline management

Full Job Description

ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com, and follow us on X or LinkedIn. We are seeking a highly skilled Contract Research Associate II with expertise in formulation to join ORIC’s formulation and drug delivery team. The successful candidate will support ORIC’s early and late-stage drug product development activities including preclinical formulation, pre-formulation and drug product analytical testing to support solid oral dose development. This person is hands-on in the laboratory and will be responsible for data collection and analysis and will present their work regularly at team meetings. The ideal candidate will be self-driven, highly organized, focused and enjoy working in a dynamic team environment. Responsibilities include and are not limited to the following: * Collaborate with Research to identify and prepare preclinical formulations. Perform supportive stability studies and develop instructions to enable reproducible formulation preparation. * Design and execution of pre-formulation studies to determine the chemical and physical properties of our small molecule drug candidates. * Analytical support for our drug products which include in-process testing of powder blends and final product testing of tablets. ## Qualification

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