ResearchAssistant

By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive. Why join Harvard Medical School? Harvard Medical School's mission is to nurture a diverse, inclusive community dedicated to alleviating suffering and improving health and well-being for all through excellence in teaching and learning, discovery and scholarship, and service and leadership. You’ll be at the heart of biomedical discovery, education, and innovation, working alongside world-renowned faculty and a community dedicated to improving human health. This is more than a job - it’s an opportunity to shape the future of medicine. The Sharpe laboratory at Harvard Medical School seeks a highly motivated individual to support research in mouse and human tumor immunology, and/or autoimmunity. Under the supervision of the Lab Manager and/or senior trainees, this individual will perform a wide range of highly sophisticated laboratory techniques, working closely with fellows and students to analyze the functions of immunoregulatory pathways. This includes immunological techniques (immune cell isolation, assays of stromal, myeloid, and T cell function, cytokine ELISA assays, multiparameter flow cytometry, handling recombinant DNA vectors), molecular biology procedures (PCR, RNA and/or DNA preparation from tissues, as well as bulk and single-cell RNASeq). Animal work is required (measuring tumors, monitoring disease scores, weighing mice, survival bleeding, i.p. / s.c. / i.v. injections, generating chimeras), mouse husbandry (colony maintenance, genotyping). This individual may also handle primary human samples (tissue dissociation, cellular isolation, immunological assays). They will analyze and summarize data, organize into lab notebooks, and report experimental results weekly. This