Amgen
Biotechnology
ProjectPortfolio&GovernanceManager
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“Project Portfolio & Governance Manager at Amgen. Skills: Project portfolio management, Master planning, Governance, Capital planning. Manage site engineering and facilities project portfolio. Provide strategic oversight of capital planning”
What You'll Achieve.
Ensure objective prioritization aligned with site strategy; Support effective oversight of projects; Ensure alignment between site strategy, regulatory expectations, resource capacity, and long‑term facility development; Support capital investment decisions; Balance project demand against available resources; Improve portfolio performance and predictability; Ensure ongoing suitability, adequacy, and effectiveness of PMO processes; Benchmark site, global, and industry portfolio performance; Strengthen delivery maturity
Industry & Context.
Manage ambiguity; Make effective decisions under pressure; Prioritise competing demands
What They're Looking For.
Must Have
Bachelor's degree in Science, Engineering, or a related discipline, Minimum of 6 years’ directly related experience in engineering, facilities, or capital project environments, At least 5 years’ leadership experience directing teams, programs, portfolios, or resource allocation, knowledge of cGMP environments, experience supporting a 24‑hour manufacturing site
Nice to Have
Formal project management qualification (PMP, IPMA, or PRINCE2 Practitioner), systems mindset with a high focus on safety, quality, compliance, and governance, Excellent communication and stakeholder-management skills within highly matrixed organizations, Demonstrated ability to identify portfolio risk, manage ambiguity, and make effective decisions under pressure, Proven capability to prioritise competing demands and clearly articulate trade‑offs and consequences, Experience mentoring, coaching, and transferring project and portfolio management expertise
What You'll Do.
Manage site engineering and facilities project portfolio
Provide strategic oversight of capital planning
Oversee project prioritization and initiation
Ensure alignment between site strategy and facility development
Lead Integrated Business Planning (IBP) PMO process
Develop and implement PMO policies and standards
Represent ADL in corporate forums
Lead Site Master Plan development and maintenance
Integrate site requirements into strategic capital plan
Perform feasibility studies
Maintain central repository for site projects
Communicate portfolio decisions and impacts
Escalate portfolio risks and constraints
Facilitate resource loading and capacity analysis
Resolve portfolio-level conflicts
Lead initiatives to improve portfolio performance
Review and improve PMO governance processes
Develop and track KPIs
Drive structured retrospectives
Foster accountability and transparency
How You'll Work.
Team & Collaboration
Collaborate with stakeholders across engineering, manufacturing, quality, and site leadership; Act as an active member of the global PMO network; Foster a culture of accountability across site project teams
Communication Scope
Excellent communication skills; Stakeholder-management skills; Clearly articulate trade-offs and consequences
Process & Methodology
Project portfolio management, Master planning, Capital planning, Project prioritization, Project initiation, Project execution, Portfolio governance, Resource planning, Capacity management, Risk management, Stakeholder management, Decision making, Sequencing, Trade-offs, Constraints management, Continuous improvement, Performance benchmarking, Lessons learned integration
Full Job Description
## **Career Category** Engineering ## ## **Job Description** ## Overview Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. With a deep and broad pipeline of potential new medicines, we continue to advance science to serve patients. Amgen Dun Laoghaire (ADL) activities include Biopharmaceutical Aseptic Manufacturing, Lyophilisation and Automated Inspection & Packaging. ## Role Purpose ## The PMO & Master Planning Specialist is a key member of the Site Facilities & Engineering (F&E) team, responsible for governance, integration, and performance of the site engineering and facilities project portfolio. The role provides strategic oversight of capital planning, project prioritisation, initiation and execution. This is done by leveraging Amgen global project management tools, methodologies, and industry best practice. The position ensures alignment between site strategy, regulatory expectations, resource capacity, and long‑term facility development through robust master planning and portfolio governance. ## Key Duties and Responsibilities The PMO & Master Planning Specialist will be the business owner of the Integrated Business Planning (IBP) PMO process. This process provides governance of the site project portfolio, ensuring objective prioritisation aligned with site strategy. Develops, implements, and sustains PMO policies, standards, and procedures to support effective oversight of projects at ADL. Leverages Amgen global tools, methodologies, and best practices, actively adopting learnings from the network and sharing ADL best practices globally. Represents ADL in corporate portfolio and project management forums and acts as an active member of the global PMO network. Site Master Planning & Strategic Capital Planning Leads the development, governance, and ongoing maintenance of the
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