Radical Numerics

AI research

ProductManager

San Francisco, California, United States; New York, New York, United States; Irvine, California, United States; Los Angeles, California, United States; Seattle, Washington, United States FULL TIME Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Mid candidates.

The Brief

“Product Manager at Radical Numerics. Skills: Product Manager, AI research, biology, product design, commercialization, general biological intelligence, platform for discovery, health, and defense, product development, user workflows, product requirements, user research, product specs, product strategy, product culture. Own product development for early Radical Numerics applications, from problem discovery through launch. Translate frontier AI capabilities into clear product concepts, workflows, ”

What You'll Achieve.

turn Radical Numerics’ frontier AI research into products that scientists, biotech teams, governments, and biosecurity organizations can actually use; define how general biological intelligence becomes a real platform for discovery, health, and defense; help define a new category: AI systems that can understand, design, and defend biology

Industry & Context.

AI research
Problems you'll solve

product instincts: you can identify real user pain, simplify complexity, and turn vague ideas into concrete workflows; translate ambiguous scientific capabilities into clear user workflows; identify the highest-leverage product opportunities; Help turn ambiguous partner conversations into concrete product opportunities and requirements

What They're Looking For.

Must Have

2–6 years of experience in product management, technical product, startup operations, or a highly analytical role, product instincts: you can identify real user pain, simplify complexity, and turn vague ideas into concrete workflows, Technical fluency, especially in AI, software, data products, developer tools, computational biology, or scientific platforms, Excellent written you can produce clear specs, product narratives, and decision documents, High ownership and bias toward you can operate without needing a fully defined roadmap, Comfort working in ambiguity, especially around emerging technology and novel markets, Ability to collaborate deeply with researchers, engineers, designers, commercial teams, and external partners, judgment around product tradeoffs, user needs, and execution priorities, Low ego, high curiosity, and willingness to learn new scientific and technical domains quickly, Excitement about building at the frontier of AI, biology, and human health

Nice to Have

Experience building AI, ML, developer tools, bioinformatics, biotech, or scientific software products, Background / exposure to biology, computational biology, genomics, biosecurity, drug discovery, or healthcare, Experience working with researchers or translating research into products, Experience at an early-stage startup or fast-moving technical organization, Familiarity with LLMs, foundation models, agents, sequence models, or multimodal AI systems, Experience designing products for technical users, scientists, or enterprise customers, Comfort with product analytics, user interviews, prototyping tools, or lightweight design workflows, Experience supporting demos, strategic partnerships, pilots, or enterprise customer discovery

What You'll Do.

Own product development for early Radical Numerics applications

from problem discovery through launch

Translate frontier AI capabilities into clear product concepts

Work closely with researchers and engineers to define product requirements

Conduct user research with scientists

biosecurity stakeholders

and strategic partners

Identify high-value use cases across health

Develop product specs

and internal decision documents

Partner with leadership on product strategy

and go-to-market priorities

Help turn ambiguous partner conversations into concrete product opportunities and requirements

Build feedback loops between users

commercial stakeholders

Drive product quality

and clarity in highly technical domains

Help shape the product culture of a frontier AI research lab

How You'll Work.

Team & Collaboration

Work closely with the CEO, research team, engineering team, and external partners; Ability to collaborate deeply with researchers, engineers, designers, commercial teams, and external partners; Build feedback loops between users, commercial stakeholders, researchers, and engineers

Communication Scope

Excellent written you can produce clear specs, product narratives, and decision documents

Process & Methodology

drive execution from concept to launch, prioritize features, drive execution, Develop product specs, wireframes, demos, launch plans, and internal decision documents, product strategy, roadmap

Full Job Description

Product Manager Location: San Francisco, CA Type: Full-time About Radical Numerics Radical Numerics is an AI research lab building general biological intelligence. Our mission is to master the language of life, and our purpose is to reduce human suffering. Our team created Evo, and started the field of generative genomics. Our work was featured on the cover of Science, and presented by our CEO on the main stage of TED2025. Evo was used to create the first AI gene therapy tool CRISPR-Cas9, and the first AI whole genome from scratch. Evo 2, featured in Nature, is the largest fully open source AI project across any domain. Radical Numerics is an AI lab bringing the rigor of distributed systems, model architecture, and numerics research to the challenges of biology. We’ve redesigned the foundation model training stack to turn the world’s raw scientific data (e. g. biological sequences, experiments, and physical processes), into intelligible, generative models that can expand and accelerate what humanity can understand, design, and cure. We are building a new type of AI research lab, driving both the frontier of biological AI for human health, and building the systems to defend against its potential misuse. The same generative breakthroughs that enable life saving cures also lowers the barrier to creating engineered threats and AI-generated bioweapons. We believe these forces are inseparable. Radical Numerics was founded to develop both the power to design and the responsibility to defend. About the Role As Product Manager, you will help turn Radical Numerics’ frontier AI research into products that scientists, biotech teams, governments, and biosecurity organizations can actually use. This is not a traditional SaaS PM role. You will operate at the intersection of AI research, biology, product design, and commercialization, helping define how general biological intelligence becomes a real platform for discovery, health, and defense. You will work closely with the CEO, re

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