Agilent Technologies

Life Science

ProcessEngineer,Upstream

$124–194k Frederick, Colorado, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Process Engineer, Upstream at Agilent Technologies. Skills: Upstream process engineering, Oligonucleotide manufacturing, Process design, Capital projects. Serve as technical lead for upstream processes. Serve as technical lead for unit operations”

What You'll Achieve.

Transform broad concepts into structured results-focused projects

Industry & Context.

Life Science
Problems you'll solve

Problem solver

Eligibility Requirements

Occasional travel

What They're Looking For.

Must Have

Bachelor's or Master's Degree in Chemical Engineering, 8+ years pharma/biopharma/fine chemicals experience, 6+ years medium to large projects experience, Experience with P&IDs, Experience with facility layouts, Experience with mass and energy balances, Experience with solvent handling, Experience with equipment design, Experience with user requirement specifications

Nice to Have

Familiarity with ASME BPE standards, Familiarity with NFPA 70 / NEC, Familiarity with International Fire and Building Code, Experience with Oligonucleotide manufacturing upstream unit operations, Experience with column packing, Experience with solid phase organic synthesis, Experience with solution preparation, Experience with reagent preparation, Experience with deprotection, Experience with ultrafiltration, Experience with organic waste systems, Experience with industrial control systems design, Experience with SCADA, Experience with PLCs, Experience with BAS, Experience with IQ/OQ/PQ protocols, Engineering skills, Communication skills, Organizational skills, Self-motivated, Hands-on problem solver, Ability to work within multi-disciplinary teams

What You'll Do.

Serve as technical lead for upstream processes

Serve as technical lead for unit operations

Perform process modeling

Perform process design review for capital projects

Develop user requirements specifications

Support P&IDs development

Support layouts development

Support equipment selection

Support equipment design

Support equipment specification

Support instrumentation specification

Support equipment selection

Support equipment procurement

Support commissioning

Support qualification

Support turn-over to manufacturing

Consult on Automation/Controls design

Consult on instrumentation selection

Consult on equipment interface

Consult on equipment module design

Consult on phase design

Support Chemical Development

Support process development

Support technology development

Support process scaleup

Support technology scaleup

Review Building Information Model (BIM)

Review process piping

Review cleanroom design

Review spatial planning

Review process startup

Execute process startup

Execute commissioning

Execute qualification

Consult on project management

Consult on project schedule

Consult on coordination of multi-disciplinary teams

Support EHS activities

Support PSM compliance

How You'll Work.

Team & Collaboration

Multi-disciplinary teams; Process development teams; Manufacturing teams; Validation teams; Quality teams; Safety teams; Project management teams

Process & Methodology

Project schedule, Budget management, Coordination

Full Job Description

## **Job Description** Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek ---\- so they can do what they do best: improve the world around us. Information about Agilent is available at [ _www.agilent.com_](http://www.agilent.com/). Want to take your knowledge and experience further? Ready to provide technical leadership and make key decisions? This is your opportunity - not only to join a committed, professional, and forward-thinking team but also to lead in the design and implementation of complex manufacturing processes and transform broad concepts into structured results-focused projects. Join a growing team with this exciting new opportunity for an expert level Upstream Process Engineer. Work on a dynamic, fast-paced, large capacity oligonucleotide API production facility design and construction project. Contribute to the growing industry of oligonucleotide (DNA-RNA) based therapeutics. Responsibilities may include but are not limited to: * Technical lead for upstream processes and unit operations. Responsible for process modeling and consulted on process fit and throughput assessments. * Responsible for process design review for large capital projects, including user requirements specifications development, P&IDs, layouts, and equipment selection. * Responsible for equipment design and procurement support, including equipment and instrumentation specification/selection, equipment procurement, FAT/SAT, installation, commissioning, qualification, and turn-over to manufacturing. * Consulted on Automation/Controls design, including instrumentation selection, equipment interface, and equipment module / phase design. * Support Chemical Development in the development, characterization, and scaleup of innovative Oligonucleotide prod

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