Agilent Technologies

Life Science

ProcessEngineer,Downstream

$124–194k Frederick, Colorado, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Senior candidates.

The Brief

“Process Engineer, Downstream at Agilent Technologies. Skills: Downstream process engineering, Oligonucleotide API production, Capital projects. Lead downstream processes. Lead unit operations”

What You'll Achieve.

Achieve manufacturing requirements

Industry & Context.

Life Science
Problems you'll solve

Problem solver

Eligibility Requirements

Occasional travel

What They're Looking For.

Must Have

Bachelor's or Master's Degree in Chemical Engineering, 8+ years pharma/biopharma/fine chemicals experience, 6+ years medium to large projects experience, Experience with P&IDs, Experience with facility layouts, Experience with mass and energy balances, Experience with solvent handling, Experience with equipment design, Experience with user requirement specifications

Nice to Have

Familiarity with ASME BPE standards, Familiarity with NFPA 70 / NEC, Familiarity with International Fire and Building Code, Experience with Oligonucleotide manufacturing downstream unit operations, Experience with Column packing, Experience with preparative liquid chromatography, Experience with buffer preparation, Experience with reaction, Experience with ultrafiltration, Experience with evaporation, Experience with drying, Experience with industrial control systems design, Experience with SCADA, Experience with PLCs, Experience with BAS, Experience with validation documentation, Experience with IQ/OQ/PQ protocols, Experience with OSHA Process Safety Management (PSM), Engineering skills, Communication skills, Organizational skills, Self-motivated, Hands-on problem solver

What You'll Do.

Lead downstream processes

Perform process modeling

Review process design

Develop user requirements specifications

Support equipment design

Support equipment procurement

Oversee commissioning

Oversee qualification

Turn over to manufacturing

Consult on Automation/Controls design

Select instrumentation

Design equipment interface

Design equipment module

Design equipment phase

Support Chemical Development

Characterize processes

Review Building Information Model

Review process startup

Execute process startup

Execute commissioning

Execute qualification

Consult on project management

Manage project schedule

Manage project budget

Coordinate multi-disciplinary teams

Support EHS activities

Ensure PSM compliance

How You'll Work.

Team & Collaboration

Multi-disciplinary teams; Process development teams; Manufacturing teams; Validation teams; Quality teams; Safety teams; Project management teams

Process & Methodology

Project schedule, Project budget

Full Job Description

## **Job Description** Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek ---\- so they can do what they do best: improve the world around us. Information about Agilent is available at [ _www.agilent.com_](http://www.agilent.com/). Want to take your knowledge and experience further? Ready to provide technical leadership and make key decisions? This is your opportunity - not only to join a committed, professional, and forward-thinking team but also to lead in the design and implementation of complex manufacturing processes and transform broad concepts into structured results-focused projects. Join a growing team with this exciting new opportunity for an expert level Downstream Process Engineer. Work on a dynamic, fast-paced, large capacity oligonucleotide API production facility design and construction project. Contribute to the growing industry of oligonucleotide (DNA-RNA) based therapeutics. Responsibilities may include but are not limited to: * Technical lead for downstream processes and unit operations. Responsible for process modeling and consulted on process fit and throughput assessments. * Responsible for process design review for large capital projects, including user requirements specifications development, P&IDs, layouts, and equipment selection. * Responsible for equipment design and procurement support, including equipment and instrumentation specification/selection, equipment procurement, FAT/SAT, installation, commissioning, qualification, and turn-over to manufacturing. * Consulted on Automation/Controls design, including instrumentation selection, equipment interface, and equipment module / phase design. * Support Chemical Development in the development, characterization, and scaleup of innovative Oligonucleotide

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