Takeda

Biotechnology

ProcessDevelopmentEngineerII,Upstream

$72–113k Lexington, Massachusetts, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Mid candidates.

The Brief

“Process Development Engineer II, Upstream at Takeda. Skills: Cell culture, Upstream development, Bioreactor operation. Execute cell culture experiments. Monitor cell culture experiments”

What You'll Achieve.

Generate high-quality data; Contribute to optimization

Industry & Context.

Biotechnology
Problems you'll solve

Evaluate trends; Support study conclusions

What They're Looking For.

Must Have

Associate's degree with 2+ years experience, Bachelor's degree in chemical engineering, biological engineering, biotechnology, biology, or related field, Experience in cell culture, Experience in upstream process development, Experience in biotherapeutics development, Hands-on experience with bioreactors, Hands-on experience with shake flasks, Hands-on experience with upstream platforms, Experience using electronic laboratory notebooks, Ability to perform basic data analysis, Ability to clearly communicate findings, Understanding of laboratory practices, Understanding of development processes, Understanding of quality requirements, Attention to detail, Ability to follow procedures, Ability to maintain accurate records, Ability to work effectively under guidance, Ability to work in a collaborative team environment

Nice to Have

DeltaV or similar process control systems experience, Technical writing skills for reports and documentation

What You'll Do.

Execute cell culture experiments

Monitor cell culture experiments

Execute upstream development experiments

Monitor upstream development experiments

Operate bioprocess equipment

Monitor bioprocess equipment

Maintain laboratory equipment

Ensure operational readiness

Partner with senior engineers

Execute larger studies

Document experimental work

Perform basic data analysis

Support study conclusions

Prepare technical summaries

Prepare study updates

Adhere to laboratory procedures

Adhere to quality standards

Adhere to safety requirements

Support continuous improvement efforts

Contribute to project tasks

Contribute to small initiatives

How You'll Work.

Team & Collaboration

Collaborate with senior process engineers; Partner with process development team

Communication Scope

Communicate findings

Full Job Description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s [Privacy Notice](https://jobs.takeda.com/privacynotice) and [Terms of Use](https://www.takeda.com/terms-and-conditions/). I further attest that all information I submit in my employment application is true to the best of my knowledge. ## **Job Description** # About the role The Process Development Engineer II supports biotherapeutics process development by executing hands-on cell culture and upstream development experiments. This role involves planning and running studies across a range of upstream unit operations, including bench-top bioreactors, Ambr microscale bioreactors, shake flasks, WAVE bioreactors, and high-throughput purification systems. You will collaborate with senior process engineers to execute complex studies while partnering closely with the broader process development team to generate high-quality data, maintain accurate documentation, and contribute to the optimization of upstream processes. This role also supports laboratory operations by ensuring equipment readiness and reliability. # How you will contribute * Execute and monitor experiments using cell culture and upstream unit operations (bench-top bioreactors, Ambr, shake flasks, WAVE bioreactors, high-throughput purification systems) * Operate and monitor bioprocess equipment using DeltaV or similar process control systems * Maintain laboratory equipment and ensure day-to-day operational readiness * Partner with senior engineers to plan and execute larger studies and experiments * Document experimental work in electronic laboratory notebooks with clear, accurate, and timely records * Perform basic data analysis to evaluate trends and support study conclusions * Prepare technical summaries and study updates to communicate findings * Adhere to laboratory procedures, quality standards, and safety

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