ProcessAnalytics&ControlResearchScientist

**Job Description** **Position Overview:** Vertex is seeking a talented individual to join our Formulation Development team in Boston, MA. Consistently and passionately challenging the boundaries of their knowledge, our Formulation Development team employs traditional and innovative analytical techniques and Quality-by-Design principles to ensure the safety, efficacy and quality of Vertex pharmaceutical products. This position provides a unique opportunity to contribute to drug product development in a dual role as a member of both the Process Analytics and Control team and the Dissolution team. The Process Analytics and Control team is responsible for the automated control strategy for drug product continuous manufacturing and the development/validation of PAT methods. Specific responsibilities include compliance to cGMPs, the development and validation of Process Analytical Technology (PAT) methods and data models, statistical data analysis including the justification for sampling plans, Monte Carlo simulations, etc., and the evaluation of new technology to support Formulation Development and Continuous GMP Manufacturing. As a member of the Dissolution team this role will also support the drug development programs at Vertex through analytical method development, validation, and transfer. This person will have the opportunity to develop and execute analytical strategies for phase appropriate dissolution methods and specification justifications. Applicants are not expected to have expertise in all aspects of both process analytics and dissolution testing but should have a strong background in analytical chemistry, chemical engineering, or pharmaceutical chemistry and the ability to grow and develop within the opportunities presented in this role. Both strong analytical technical capabilities and excellent communication skills are required to be successful in this role. **Key Duties and Responsibilities:** **_PAT responsibilities:_** * Developing PAT methods (multiva