Roche
Healthcare
PrincipalStatisticalMethodologyDataScientist
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“Principal Statistical Methodology Data Scientist at Roche. Skills: Statistical methodology, Advanced analytics, Clinical trial research, Statistical computing. Serve as methodological thought partner. Provide expert guidance”
What You'll Achieve.
Improve decision-making; Elevate analytical excellence
Industry & Context.
Quantitative analysis; Methodological problem solving
What They're Looking For.
Must Have
PhD or equivalent experience, 7+ years experience, Advanced analytics experience, Biomedical data experience, Clinical trial research experience, Statistical computing expertise, Advanced modeling expertise, Develop novel analytical solutions, Develop custom analytical solutions, Mentoring experience, Contribute to internal standards, Contribute to strategy, Contribute to capability development, Respect cultural differences
Nice to Have
Develop fit-for-purpose analytical methods, Design scalable workflows, Design scalable frameworks, Influence portfolio decisions, Influence program decisions, Publications, Presentations, Internal white papers, Thought leadership emerging data science, AI/ML translational research, Real-world data integration, Predictive biomarkers
What You'll Do.
Serve as methodological thought partner
Provide expert guidance
Lead methodology development
Lead methodology institutionalization
Improve decision-making
Shape understanding of statistical methods
Consult on statistical methods
Publish on statistical methods
Lead education efforts
Anticipate regulatory trends
Anticipate industry shifts
Integrate methodologies
Guide external engagements
Act as connector across teams
Surface recurring challenges
Co-create scalable solutions
Elevate analytical excellence
Drive external collaboration
Participate in consortia
Participate in working groups
Participate in regulatory initiatives
Influence strategic direction
Enable adoption of methodologies
Drive scientific rigor
Drive decision-making excellence
Consult on methodological needs
Educate on methodological needs
Outreach on methodological needs
Apply innovative methods
Apply appropriate methods
Prototype estimand frameworks
Prototype trial simulations
Prototype covariate adjustment strategies
Support scalable adoption
Perform portfolio-level analyses
Perform scenario modeling
Inform go/no-go decisions
Optimize clinical strategy
Maintain external relationships
Represent company in consortia
Represent company in working groups
Represent company in regulatory collaborations
Stay at forefront of advances
How You'll Work.
Team & Collaboration
Cross-functional stakeholders; Project teams; Biostatisticians
Communication Scope
Publications; Presentations
Full Job Description
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. ### ### The Position The **Statistical Methodology Data Scientists** play a strategic role in enabling the adoption of fit-for-purpose statistical methodologies to drive scientific rigor and decision-making excellence. This team serves as a center of excellence focused on consultation, education, and outreach to ensure that innovative and appropriate methods are applied across programs and portfolios. Statistical Methodology Data Scientists collaborate closely with project teams, biostatisticians, and cross-functional stakeholders to identify methodological needs, prototype solutions (e.g., estimand frameworks, trial simulations, covariate adjustment strategies), and support scalable adoption through training, templates, and open source software/tools. They engage in portfolio-level analyses, scenario modeling, and quantitative frameworks that inform go/no-go decisions and optimize clinical strategy. The team also maintains key external relationships, representing the company in consortia, scientific working groups, and regulatory collaborations to stay at the forefront of methodological advances in the pharmaceutical industry. **The Opportunity:** * You serve as a methodological thought partner to study teams, providing expert guidance on complex design and analysis across programs * You lead the development and institutionalization of methodologies that improve decision-making at trial and portfolio levels (e.g., quantitative go/no-go criteria, simulation frameworks, model-based projections) * You shape cross-fu
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