Medtronic

Healthcare Technology

PrincipalSoftwareEngineer-Signals&AlgorithmInterfaces(Python/C++)

$153–229k Newton, Massachusetts, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Principal candidates.

The Brief

“Principal Software Engineer - Signals & Algorithm Interfaces (Python/C++) at Medtronic. Skills: Architecture for algorithm integration, Real-time signal pipelines, Algorithm execution frameworks, Python, C++. Set the technical direction for how the Affera Signals & Algorithms team's work is brought into the Prism Mapping platform. Lead cross-cutting design for real-time signal pipelines, algorithm execution frameworks, and the optimization strategies that let algorithms hit clinical performance ”

What You'll Achieve.

How quickly new clinical capabilities reach physicians; How reliably they perform in the lab; Raise team productivity and quality

Industry & Context.

Healthcare Technology
Problems you'll solve

Drive root cause on the hardest cross-domain problems; Exercise broad technical judgment in defining approaches to complex system and architectural problems with limited oversight; Experience solving ambiguous, high-impact technical problems spanning multiple domains or subsystems

Eligibility Requirements

Minimum of 4 days a week onsite, U. S. work authorization sponsorship is offered exclusively for Principal-level roles and above, Physical job requirements are representative of those that must be met by an employee to successfully perform the essential functions of this job

What They're Looking For.

Must Have

Bachelor's degree and a minimum of 7 years of relevant experience, OR Master's degree with a minimum of 5 years of relevant experience, OR PhD with 3 years relevant experience

Nice to Have

Deep expertise architecting real-time signal and algorithm pipelines for production systems, understanding of DSP fundamentals and the constraints they impose on system architecture — latency, determinism, sample integrity, Track record of building research-to-production pathways for algorithm work, Deep expertise in Python and C++ and in software architecture for complex, multi-component systems, Proven experience delivering complex, real-time, device-integrated, or networked systems, Experience leading large, complex, cross-functional technical initiatives, Experience defining architecture, standards, or technical direction across multiple components or teams, Experience solving ambiguous, high-impact technical problems spanning multiple domains or subsystems, Experience influencing technical decisions beyond immediate team boundaries, Experience in regulated environments preferred, Advances how the team uses AI tools — introduces new approaches that raise team productivity and quality

What You'll Do.

Set the technical direction for how the Affera Signals & Algorithms team's work is brought into the Prism Mapping platform

Lead cross-cutting design for real-time signal pipelines

algorithm execution frameworks

and the optimization strategies that let algorithms hit clinical performance targets at scale

Partner deeply with the Signals & Algorithms team

and clinical experts to shape roadmaps

mentor senior engineers across the integration space

and drive root cause on the hardest cross-domain problems

Lead architecture for algorithm integration on the Prism Mapping platform — real-time signal pipelines

algorithm execution frameworks

and the data contracts that connect hardware

Define multi-release direction for the algorithm integration architecture and the team partnership model behind it

Set the engineering bar for algorithm-adjacent code on real-time guarantees

and clinical performance

Lead the design and delivery of major subsystems

cross-cutting architecture

or large technical initiatives

Exercise broad technical judgment in defining approaches to complex system and architectural problems with limited oversight

Drive technical alignment across software

and other cross-functional teams

Establish and promote software design patterns

engineering standards

and development best practices

Provide technical leadership across teams through mentoring

and guidance on critical engineering decisions

Identify and drive improvements in architecture

development processes

Shape the technical roadmap and architectural direction for major subsystems or product capabilities

Communicate complex technical tradeoffs

and recommendations to stakeholders across functions

How You'll Work.

Team & Collaboration

Partner deeply with the Signals & Algorithms team, hardware engineers, and clinical experts; Drive technical alignment across software, systems, quality, product, and other cross-functional teams; Provide technical leadership across teams through mentoring, design reviews, and guidance on critical engineering decisions; Communicate complex technical tradeoffs, risks, and recommendations to stakeholders across functions

Communication Scope

Communicate complex technical tradeoffs, risks, and recommendations to stakeholders across functions

Process & Methodology

Lead the design and delivery of major subsystems, cross-cutting architecture, or large technical initiatives

Full Job Description

We anticipate the application window for this opening will close on - 15 Jun 2026 At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world. # **A Day in the Life** At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges are invaluable to our work. We’re working a minimum of 4 days a week onsite as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary. As a Principal Software Engineer – Signals & Algorithm Interfaces (Python/C++) you will set the technical direction for how the Affera Signals & Algorithms team's work is brought into the Prism Mapping platform — the architecture that lets new algorithms reach the clinic safely and performantly, and the partnership model that connects algorithm development to production engineering. You'll lead cross-cutting design for real-time signal pipelines, algorithm execution frameworks, and the optimization strategies that let algorithms hit clinical performance targets at scale. You'll partner deeply with the Signals & Algorithms team, hardware engineers, and clinical experts to shape roadmaps, mentor senior engineers across the integration space, and drive root cause on the hardest cross-domain problems — the ones that span signal behavior, system code, and clinical workflow. Your decisions will determine how quickly new clinical capabilities reach physicians, and how reliably they perform in the lab. ** _About the Affera Prism Mapping System_ ** The Affera Prism Mapping System is an advanced electrophysiology mapping platform used by physicians to diagnose and guide the treatment of cardiac arrhythmias. It captures and processes signals from inside the beating heart, bu

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