PrincipalSoftwareEngineerII

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. ### ### The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche. We are seeking an architect-level Principal Software Engineer II to lead the software evolution of Roche’s proprietary sequencing technology, SBX. In this role, you will bridge the gap between experimental data science and industrial software engineering. While you will still engage with the "science" of DNA sequencing, your primary mandate is to engineer the systems that make that science scalable, reproducible, and fast. You will serve as the Technical Lead for a hybrid squad, driving the transition of experimental AI/models from Jupyter notebooks into robust, version-controlled, and highly optimized production libraries running on high-performance infrastructure. ### You will define the software architecture for SBX data analysis. You are not just analyzing data; you are building the engine that processes it. You will ensure that our basecalling and sequencing algorithms are not only accurate but are also performant, maintainable, and deployable at scale. **The Opportunity** * Define and enforce software engineering standards, including clean code practices, comprehensive unit/integration testing, and mandatory code reviews within the data science team. * Develop modular and extensible software libraries for DNA analys