PostdoctoralResearcher

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto. UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality. [www.uhn.ca](https://www.uhn.ca/) Union: Non-Union Number of Vacancies: 1 New or Replacement Position: Replacement Site: Princess Margaret Cancer Research Tower Department: Research Reports To: Principal Investigator Salary Range: $54,902 - $93,333 Per Year Hours: 37.5 Hours Per Week Shifts: Monday - Friday Status: Temporary Full-time (1-Year Contract) Closing Date: June 24, 2026 Position Summary: A Postdoctoral Researcher position is available in the laboratory of Dr. Steven Chan at the Princess Margaret Cancer Centre. The Chan Laboratory studies the biology of acute myeloid leukemia (AML), leukemic stem cells, and clonal hematopoiesis (CH), with a strong translational focus on discovering and exploiting novel therapeutic vulnerabilities in pre-malignant and malignant myeloid cells. This project will define the genetic and synthetic-lethal interactions of high-risk clonal hematopoiesis mutations, including TP53 and spliceosome (splicing factor) mutations, that drive the progression of C