Biohub
Biotechnology
PostdoctoralFellow,MicrotissueSignalingDynamics
Neural analysis suggests this role is
optimal for Mid+ candidates.
“Postdoctoral Fellow, Microtissue Signaling Dynamics at Biohub. Skills: Microfluidics, Quantitative biology, Experimental design, Data analysis. Develop microfluidic platforms. Develop code to operate system components”
What You'll Achieve.
Uncover core mechanisms; Develop effective therapeutic strategies; Develop transformative measurement technologies
Industry & Context.
Tackle complex biological questions
What They're Looking For.
Must Have
Programming including Matlab, Programming including python, Programming including C++, Cleanroom/Soft lithography experience, Multilayer microfluidic device fabrication, Experience handling mammalian cell, Experience handling tissues, Experience with advanced microscopy, Image analysis
Nice to Have
Confocal microscopy experience, Light-sheet microscopy experience
What You'll Do.
Develop microfluidic platforms
Develop code to operate system components
Perform experiments to simulate disease scenarios
Analyze sequential volumetric images
Analyze cytokines profiles
Analyze protein profiles
Collaborate with other teams
How You'll Work.
Team & Collaboration
Interdisciplinary teams; Integrated experimental data; Computational approaches
Full Job Description
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team We study how cells within tissues communicate through biochemical signals during disease and immune responses. By collecting multimodal data from tissues and developing advanced microfluidic platforms, we aim to uncover the core mechanisms that drive disease progression and treatment responses. Integrating experimental data with computational approaches—including network modeling, information theory, and machine learning—we seek to identify the most informative indicators of disease state and develop more effective therapeutic strategies for autoimmune diseases and cancer. The Opportunity Biohub Chicago seeks outstanding early-career experimental scientists with expertise in microfluidics and quantitative biology to join as a Postdoctoral Fellow developing innovative devices for culturing and testing various tissues. We welcome candidates from diverse experimental backgrounds—whether rooted in microfluidics, imaging, bioengineering, or other modalities—who bring rigorous quantitative thinking and a drive to tackle complex biological questions. This role offers a unique opportunity to work hands-on in a generously funded, highly collaborative environment at the intersection of technology development, bioengineering, and disease-focused discovery. Postdoctoral Fellows will be embedded in interdisciplinary teams applying and developing microfluidic devices to simulate various inflammatory disease mechanisms with focus on skin tissue and/or gut tissue model. The successful candidate will design an
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