Vertex

Biotechnology

PharmacologyResearchScientist,ExVivo

$111–166k Boston, Massachusetts, United States FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Mid+ candidates.

The Brief

“Pharmacology Research Scientist, Ex Vivo at Vertex. Skills: Pharmacology research, Assay development. Design preclinical PK assays. Optimize preclinical PK assays”

Industry & Context.

Biotechnology
Problems you'll solve

Problem solving; Troubleshooting

What They're Looking For.

Must Have

10 years industry experience (Bachelor's), 5 years industry experience (Master's), 3 years industry experience (PhD)

What You'll Do.

Design preclinical PK assays

Optimize preclinical PK assays

Execute preclinical PK assays

Optimize immunoassays

Adapt standardized workflows

Create standardized workflows

Research answers independently

Communicate across functions

Work across functions

Author Bioanalytical reports

Review Bioanalytical reports

Analyze experimental data

Interpret experimental data

Present experimental data

How You'll Work.

Team & Collaboration

Across functions; Within functions

Communication Scope

Written communication; Verbal communication; Presenting data

Full Job Description

**Job Description** **General Summary:** The CGT Pharmacology group in Boston is seeking a highly motivated and innovative **Pharmacology Research Scientist** to work collaboratively across the Research organization by supporting pharmacology efforts to understand the pharmacokinetics, pharmacodynamics, and efficacy of novel cell and gene therapies in disease models. The successful candidate will focus on developing, optimizing and validating PK/PD assays, immunoassays, custom multiplexes, and primary cell/explant assays supporting both early discovery and IND-enabling phases. This role requires a specialized technical expert in assay development (e.g. immunoassays, cell assays, flow assays, etc.) who can lead work streams, prioritize data integrity/documentation and mentor others within the team. Strong technical and problem-solving skills, self-motivation, presentation/communication skills, and the ability to both leads, as well as thrive as part of a team are essential. **Key Duties and Responsibilities:** * Designs, optimizes and executes preclinical PK, and immunoassay and cell assays to support pharmacology research efforts * Uses a high level of scientific judgment and creative thinking to adapt and/or create standardized workflows & protocols by applying breadth of knowledge and prior work experience. * Takes ownership of daily tasks, researching answers and contacting other subject matter experts independently before soliciting support from senior team members. * Exercises emerging judgment to prioritize workload, based on project impact. * Communicate and work collaboratively within and across functions to support programs from early discovery through preclinical proof of concept and candidate selection to advance the company pipeline. * Authors and reviews Bioanalytical reports for regulatory filings * Analyze, interpret, and present experimental data to project teams and senior leadership. * Possesses a strong understanding of the drug development proces

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