Biohub SF, LLC
Biomedical research
OpticalEngineer,AdvancedLightSheetMicroscopy
Neural analysis suggests this role is
optimal for Mid+ candidates.
“Optical Engineer, Advanced Light Sheet Microscopy at Biohub SF, LLC. Skills: Light sheet microscopy, Optical engineering, Hardware control, Automation. Design, prototype, implement, and optimise custom subsystems. Integrate mechanical, thermal, fluidic, optical, and electronic components”
Industry & Context.
Troubleshoot complex mechanical systems; Troubleshoot complex electrical systems; Troubleshoot complex software systems
What They're Looking For.
Must Have
Master of Science, or PhD degree, at least 5 years practical engineering skills, at least 4 years solid working knowledge of electronics, at least 3 years CAD design experience, programming experience in C/C++/Rust, Proven experience developing hardware control scripts, Proven ability to troubleshoot complex systems, communication skills, collaborative ability to work effectively
Nice to Have
Experience with C/C++/Rust desired, Knowledge and experience in light-sheet microscopy, Experience or interest in integrating Adaptive Optics, Experience with feedback control systems, Experience designing or integrating thermal control, Experience and deep understanding of low-level coding, Familiarity with high-performance computing concepts, Familiarity with Linux-based systems, Familiarity with optical metrology, Experience working in a biological or life sciences research environment
What You'll Do.
and optimise custom subsystems
and electronic components
Develop modular hardware control software
Interface with cameras
Design and implement automated imaging protocols
Incorporate feedback loops
Implement new features and capabilities
Contribute to data acquisition workflows
Handle large-scale imaging datasets
Document system architectures
Document mechanical designs
Document assembly procedures
How You'll Work.
Team & Collaboration
Multidisciplinary team; Computer scientists; Optical engineers; Biologists; Scientists; Bioengineers
Full Job Description
Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health. Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work here. Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We a
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