Fusion Pharmaceuticals

Pharmaceuticals

MicrobiologyLaboratorySupervisorRadioConjugateLaboratory

CA$86–113k Hamilton, Ontario, Canada FULL TIME
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Supervisor candidates.

The Brief

“Microbiology Laboratory Supervisor — Radio Conjugate Laboratory at Fusion Pharmaceuticals. Skills: Microbiological control, Aseptic manufacturing, Regulatory compliance, Radiopharmaceuticals. Lead microbiology team. Supervise daily lab operations”

Industry & Context.

Pharmaceuticals
Problems you'll solve

Root cause analysis

Eligibility Requirements

Work extended shifts, Work weekends, Work holidays, After-hours support, On-site presence, <5% travel

What They're Looking For.

Must Have

Bachelor's degree in Microbiology, 5–8 years supervising laboratory teams, Hands-on environmental monitoring, Contamination control experience, Cleanroom operations experience, Regulatory compliance experience, Work in designated labs, Work in isolators/hot cells

Nice to Have

Experience in radiopharmaceutical environments

What You'll Do.

Lead microbiology team

Supervise daily lab operations

Drive continuous training

Oversee aseptic process design

Oversee aseptic process simulation

Establish environmental monitoring

Maintain environmental monitoring

Analyze environmental monitoring

Perform trend analysis

Conduct contamination risk assessments

Maintain Contamination Control Strategy

Monitor cleanroom operations

Ensure GMP compliance

Ensure best aseptic practices

Ensure effective microbiological controls

Act as SME for regulations

Lead contamination event investigations

Lead root cause analysis

Implement process improvements

Work with cross-functional teams

Oversee EM for radiopharmaceuticals

Oversee bioburden for radiopharmaceuticals

Oversee sterility assurance for radiopharmaceuticals

Advise on interventions in isolators/hot cells

Ensure contamination control solutions

Design sampling plans for radiopharmaceuticals

Supervise sampling plans for radiopharmaceuticals

How You'll Work.

Team & Collaboration

Cross-functional teams; Quality; Engineering; Production; Validation

Full Job Description

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next generation radioconjugates (RCs) as precision medicines. Fusion has multiple pipeline programs entering early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radioconjugate manufacturing facility to meet the demand for our growing pipeline of RCs. **Overview** The Microbiology Supervisor is responsible for leading and supervising all aspects of microbiological control in a regulated aseptic manufacturing environment, with a focus on sterile radiopharmaceutical products. This role combines technical microbiology expertise with hands-on supervisory responsibilities, ensuring robust contamination control, high-quality environmental monitoring, radiological controls and compliance with global regulatory standards (including EU Annex 1 and GMP). Other duties can be assigned as required. **Responsibilities** * Microbiology Leadership: Lead and mentor the microbiology team, supervising daily lab operations and resource planning to meet manufacturing and clinical/commercial supply timelines; manage workload and performance, and drive continuous training to maintain meticulous quality and compliance standards. * Aseptic Process & Risk Assessment: Oversee aseptic process design and simulation, risk assessments, evaluate changes, ensuring compliance with regulatory requirements. * Environmental Monitoring: Establish, maintain, and analyze environmental monitoring programs and EMPQ, perform trend analysis and conduct contamination risk assessments. * Contamination Control: Maintain the site’s Contamination Control Strategy (CCS), including cleanroom zoning, gowning, and disinfectant program

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