Company
MedicinalChemist(f/m/x)
Neural analysis suggests this role is
optimal for Mid candidates.
“Medicinal Chemist (f/m/x). Skills: Medicinal Chemistry, Organic Chemistry, Chemical Biology. Designing molecular probes. Developing molecular probes”
What You'll Achieve.
optimize probe stability; optimize probe binding; optimize probe selectivity; optimize probe assay compatibility
Industry & Context.
Troubleshooting and resolving technical issues
What They're Looking For.
Must Have
PhD in medicinal chemistry, organic chemistry, chemical biology or a comparable discipline, At least 2 years of professional experience in drug-like small molecule design, bioconjugation, or targeted probe development in an industrial or start up environment, Design and synthesis of small molecules and linkers, Conjugation strategies for proteins or antibodies, Biophysical and biochemical characterization of conjugates
Nice to Have
experience interfacing with in vivo studies is a plus, German and Chinese are a plus
What You'll Do.
Designing molecular probes
Developing molecular probes
Conducting in vitro studies
Interpreting in vitro studies
Optimizing probe stability
Identifying project risks
Assessing project risks
Developing mitigation strategies
Troubleshooting technical issues
Resolving technical issues
Reporting project progress
How You'll Work.
Team & Collaboration
Collaborating with cell biologists; Collaborating with engineers; Collaborating with application experts; working in interdisciplinary teams; working in cross functional teams; Supporting further evaluation; collaboration with internal partners; collaboration with external partners
Communication Scope
Excellent communication skills; reporting on project progress to management; reporting on project progress to stakeholders
Process & Methodology
Identifying project risks, Assessing project risks, Developing mitigation strategies
Full Job Description
# **Your Role** * Designing and developing molecular probes, including the linker components. * Collaborating with cell biologists, engineers and application experts to define probe requirements and performance specifications. * Conducting and interpreting in vitro studies (e.g. binding, selectivity, stability) to optimize probe performance; * Supporting further evaluation in collaboration with internal and external partners * Identifying and assessing project risks and developing mitigation strategies. * Troubleshooting and resolving technical issues related to linker chemistry, stability, and assay compatibility. * Keeping up to date of industry and academic trends in targeted probe technologies. * Documenting results clearly and reporting on project progress to management and stakeholders. # **Your Profile** * PhD in medicinal chemistry, organic chemistry, chemical biology or a comparable discipline. * At least 2 years of professional experience in drug-like small molecule design, bioconjugation, or targeted probe development in an industrial or start up environment. * Demonstrated expertise in: Design and synthesis of small molecules and linkers. Conjugation strategies for proteins or antibodies. Biophysical and biochemical characterization of conjugates * Familiarity with in vitro assay data and their use in property optimization; experience interfacing with in vivo studies is a plus. * Excellent communication skills and enjoyment of working in interdisciplinary, cross functional teams. * Very good written and spoken English skills; German and Chinese are a plus. Your ZEISS Recruiting Team: Friederike Kirklar-Harms
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