Xenon Pharmaceuticals
Biotech
Manager/SeniorManager,TrialOperations
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“Manager/Senior Manager, Trial Operations at Xenon Pharmaceuticals. Skills: Trial operations leadership, Clinical trial management, Vendor management, Budget oversight. Provide clinical trial management leadership. Collaborate with cross-functional team members”
What You'll Achieve.
Deliver critical milestones on time; Deliver critical milestones within budget
Industry & Context.
Risk assessment; Mitigation strategies; Contingency planning
5-10% travel
What They're Looking For.
Must Have
Project management experience, Organizational skills, Ability to work independently, Ability to work collaboratively, Good judgement, Flexibility, Detail oriented
Nice to Have
Previous experience with CTA and IND submissions preferred
What You'll Do.
Provide clinical trial management leadership
Collaborate with cross-functional team members
Coordinate proposal evaluation
Provide input into selection and contracting
Manage contracted service providers
Lead investigator and site selection
Review and oversee study budgets
Manage study timelines
Conduct risk assessments
Develop mitigation strategies
Develop contingency planning
Communicate with internal/external teams
Mitigate/resolve challenges
Participate in clinical trial operations
Coordinate clinical trial protocols
Write clinical trial protocols
Review clinical trial protocols
Finalize clinical trial protocols
Coordinate consent forms
Finalize consent forms
Coordinate study plans
Coordinate safety reviews
Review safety reviews
Finalize safety reviews
Coordinate essential regulatory documents
Write essential regulatory documents
Review essential regulatory documents
Finalize essential regulatory documents
Share trial conduct best practices
Implement trial conduct best practices
Oversee adherence to regulations
How You'll Work.
Team & Collaboration
Cross-functional team members; Internal/external teams; Multidisciplinary team
Communication Scope
Verbal communication; Written communication
Process & Methodology
Project management, Timeline management, Budget management, Milestone delivery
Full Job Description
Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE https://www.nasdaq.com/market-activity/stocks/xene) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline https://xenon-pharma.com/pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are important pain targets. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neur
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