Natera

Personalized Oncology Diagnostics

MachineLearningScientist,MultimodalAI

$125–156k United States Remote Friendly
Market Sentiment
HIGH DEMAND

Neural analysis suggests this role is
optimal for Mid+ candidates.

The Brief

“Machine Learning Scientist, Multimodal AI at Natera. Skills: Deep Learning, Multimodal AI, Machine Learning, PyTorch. Design deep learning models. Implement deep learning models”

What You'll Achieve.

Advance personalized oncology diagnostics; Advance tumor-informed minimal residual disease (MRD) testing

Industry & Context.

Personalized Oncology Diagnostics
Problems you'll solve

Develop multimodal AI systems; Scale machine learning approaches; Translate machine learning prototypes

What They're Looking For.

Must Have

PhD in Computer Science, Computational Biology, Biomedical Engineering, Bioinformatics, Statistics, or a related quantitative discipline with a focus on machine learning or AI, Core experience developing machine learning models for biomedical applications, specifically in medical imaging, computational pathology, genomics, transcriptomics, multi-omics, or molecular diagnostics, Hands-on expertise with PyTorch, production-level programming skills in Python, Practical application of deep learning architectures such as CNNs, transformers, attention mechanisms, and representation learning, Experience managing datasets and training workflows within distributed or cloud computing environments (AWS), Proven ability to take ownership of research projects and translate prototypes into robust, deployment-ready workflows, Experience adapting pre-trained foundation models for downstream biomedical applications

Nice to Have

Experience integrating imaging, molecular, and clinical data within unified multimodal machine learning frameworks, Technical familiarity with DNA sequencing, RNA sequencing, methylation, and ctDNA assays, Hands-on experience with digital pathology software and whole-slide imaging analysis, Exposure to survival modeling, longitudinal prediction, or time-to-event modeling, Experience applying self-supervised learning, weakly supervised learning, or multiple instance learning (MIL) to clinical data, Domain knowledge in oncology, biomarker discovery, or clinical precision medicine, Track record of peer-reviewed publications in machine learning or computational biology conferences and journals (e. g. , NeurIPS, ICML, CVPR, MICCAI, Nature Biomedical Engineering)

What You'll Do.

Design deep learning models

Implement deep learning models

Evaluate deep learning models

Develop multimodal AI architectures

Build machine learning workflows

Apply machine learning techniques

Collaborate with teams

Analyze model outputs

How You'll Work.

Team & Collaboration

Collaborate with scientists, pathologists, bioinformaticians, and software engineers; Collaborate across technical and clinical teams; Communicate data-driven findings clearly to cross-functional stakeholders; Inclusive collaboration

Communication Scope

Communicate data-driven findings clearly

Process & Methodology

Take ownership of research projects

Full Job Description

POSITION SUMMARY: Natera is hiring a Machine Learning Scientist to join our AI and computational biology team. This role develops and deploys deep learning models across digital pathology, genomics, transcriptomics, and cell-free DNA (cfDNA) modalities. You will build multimodal AI systems that integrate imaging, molecular, and clinical data, leveraging proprietary genomic and clinical datasets. You will collaborate with scientists, pathologists, bioinformaticians, and software engineers to scale machine learning approaches that advance personalized oncology diagnostics and tumor-informed minimal residual disease (MRD) testing. PRIMARY RESPONSIBILITIES: Design, implement, and evaluate deep learning models across biomedical data modalities, including histopathology imaging, genomic sequencing, transcriptomics, and cfDNA features Develop multimodal AI architectures that integrate H&E whole-slide imaging data with molecular and clinical data sources Build scalable, production-quality machine learning workflows and pipelines using cloud infrastructure (AWS) Apply modern machine learning techniques including convolutional neural networks (CNNs), vision transformers (ViTs), sequence transformers, representation learning, and foundation model fine-tuning Collaborate across technical and clinical teams to translate machine learning prototypes into validated tools Analyze model outputs to generate reproducible biological and clinical insights Document pipelines thoroughly and communicate data-driven findings clearly to cross-functional stakeholders QUALIFICATIONS: PhD in Computer Science, Computational Biology, Biomedical Engineering, Bioinformatics, Statistics, or a related quantitative discipline with a focus on machine learning or AI Core experience developing machine learning models for biomedical applications, specifically in medical imaging, computational pathology, genomics, transcriptomics, multi-omics, or molecular diagnostics Hands-on expertise with PyTorch and str

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